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卫星透析单元中的血液透析:患者回流至中心透析单元的发生率。

Hemodialysis in satellite dialysis units: incidence of patient fallback to the in-center dialysis unit.

作者信息

Barthelemy Aurore, Lobbedez Thierry, Bechade Clemence, Henri Patrick, Batho Jean-Marie, Cardineau Eric, Jeanson Alain, Landru Isabelle, Lefort Françoise, Potier Jacky, Zagdoun Elie, Thibon Pascal

机构信息

Renal Epidemiology and Information Network, CHU de Caen, 14000, Caen, France.

出版信息

J Nephrol. 2015 Aug;28(4):485-93. doi: 10.1007/s40620-014-0153-1. Epub 2014 Oct 25.

Abstract

BACKGROUND

Patient fallbacks occur when a patient treated in a satellite dialysis unit (SDU) must be transferred to an in-center dialysis unit. Fallbacks have an impact on the in-center dialysis unit organization. This study was carried out to estimate the incidence and risk factors of patient fallback.

METHODS

Between 01/01/2006 and 31/12/2010 there were 193 patients starting dialysis in SDUs in one French region. The primary outcome was the incidence of temporary and permanent fallbacks with or without hospitalization. A survival analysis and binomial negative regression were used for the statistical analysis.

RESULTS

Among the 193 patients, 117 (60.6%; 95% confidence interval [CI]: 53.3-67.6) had at least one fallback, which occurred within a median of 249 days (interquartile range [IQR]: 71-469) after the first session in the SDU. The median number of fallbacks by subject was 1 (IQR: 0-4). The median duration of the fallback period was 4 days (IQR: 1-8) and median number of dialysis sessions during the fallback time was 1 (IQR: 1-3). Of the 494 temporary fallbacks, 210 were due to patient hospitalization, the main cause of which was cardiovascular disease. At univariate analysis, patients permanently transferred to in-center hemodialysis units were older, had more peripheral arteriopathy, cancer and arrhythmia. At multivariate analysis, peripheral arteriopathy (relative risk [RR] 2.06, 95% CI 1.05-4.09) and the center (center 2: RR 0.42, 95% CI 0.21-0.84; center 3: RR 2.88, 95% CI 1.20-6.91) were significantly associated with the number of fallbacks.

CONCLUSION

Fallback is a common event in hemodialysis patients treated in SDUs. Yet, the SDU system operates well since a third of patients treated in these units are still in SDUs at 2 years of follow-up. Factors associated with patient fallback are the center and cardiovascular disease.

摘要

背景

当在卫星透析单元(SDU)接受治疗的患者必须转至中心透析单元时,就会发生患者回退情况。回退会对中心透析单元的组织产生影响。本研究旨在评估患者回退的发生率及危险因素。

方法

在2006年1月1日至2010年12月31日期间,法国某地区有193例患者在卫星透析单元开始透析治疗。主要结局指标为伴有或不伴有住院治疗的临时和永久回退的发生率。采用生存分析和二项式负回归进行统计分析。

结果

在这193例患者中,117例(60.6%;95%置信区间[CI]:53.3 - 67.6)至少发生过一次回退,回退发生在卫星透析单元首次治疗后的中位时间249天(四分位数间距[IQR]:71 - 469)。每位患者回退的中位次数为1次(IQR:0 - 4)。回退期的中位持续时间为4天(IQR:1 - 8),回退期间透析治疗的中位次数为1次(IQR:1 - 3)。在494次临时回退中,210次是由于患者住院,主要原因是心血管疾病。单因素分析显示,永久转至中心血液透析单元的患者年龄更大,外周动脉病变、癌症和心律失常更多见。多因素分析显示,外周动脉病变(相对危险度[RR] 2.06,95% CI 1.05 - 4.09)和中心(中心2:RR 0.42,95% CI 0.21 - 0.84;中心3:RR 2.88,95% CI 1.20 - 6.91)与回退次数显著相关。

结论

在卫星透析单元接受治疗的血液透析患者中,回退是常见事件。然而,卫星透析单元系统运行良好,因为在这些单元接受治疗的患者中有三分之一在随访2年时仍留在卫星透析单元。与患者回退相关的因素是中心和心血管疾病。

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