von Bülow Anna, Backer Vibeke, Porsbjerg Celeste
Lungemedicinsk Forskningsenhed, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400 København NV.
Ugeskr Laeger. 2014 Jan 13;176(3A):V05130307.
Severe asthma is defined by persistent symptoms and frequent exacerbations despite intensive asthma therapy. The prevalence is estimated to be 5-10% of all asthmatics. Severe asthma is responsible for a major burden of illness including low quality of life and a disproportionate use of health-care resources. The clinical assessment of severe asthma must include verification of the correct diagnosis, adherence to medication, excluding differential diagnosis and identification and treatment of aggravating co-morbidities and trigger factors.
重度哮喘的定义为尽管接受了强化哮喘治疗仍有持续症状和频繁发作。据估计，重度哮喘在所有哮喘患者中的患病率为5%-10%。重度哮喘导致了重大的疾病负担，包括生活质量低下和医疗资源的过度使用。重度哮喘的临床评估必须包括核实正确诊断、药物依从性、排除鉴别诊断以及识别和治疗加重的合并症和触发因素。
