Pan Kl, Chan Wh, Shanmugam P, Ong Gb, Kamaruddin F, Tan S
Department of Orthopaedics, Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, Kuching, Malaysia.
Department of Paediatric Oncology, Sarawak General Hospital, Kuching, Malaysia.
Malays Orthop J. 2014 Mar;8(1):32-6. doi: 10.5704/MOJ.1403.015.
Patients with extensive malignancies involving the femur often require total femoral replacement when their limbs can be salvaged. Reported series are small and involve heterogeneity of tumours. We present nine patients with osteosarcomas of the femur treated at our institution between 2003 and 2010 with a mean follow-up of 27 (6 to 56) months. Their ages ranged from 9 to 17 (mean 14 years). They had large volume tumours (mean 911 cm3) and presented late with a mean of 5.5 months from the onset of symptoms to definitive treatment. All patients underwent resection and total femur replacement. Six patients have died and two are alive with good function at the time of this report. One was lost to follow-up. These patients require a high level of treatment care and have a guarded prognosis.
Large osteosarcomas, femur, total femoral replacement.
患有累及股骨的广泛恶性肿瘤的患者,若其肢体能够挽救,通常需要进行全股骨置换。已报道的病例系列规模较小且肿瘤类型各异。我们报告了2003年至2010年间在我院接受治疗的9例股骨骨肉瘤患者,平均随访时间为27(6至56)个月。他们的年龄在9至17岁之间(平均14岁)。他们患有大体积肿瘤(平均911立方厘米),且从症状出现到最终治疗的平均时间为5.5个月,就诊较晚。所有患者均接受了切除和全股骨置换手术。截至本报告时,6例患者已死亡,2例存活且功能良好,1例失访。这些患者需要高水平的治疗护理,预后不佳。
大型骨肉瘤、股骨、全股骨置换