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无角牦牛(Bos grunniens)线粒体基因组的完整序列。

The complete sequence of mitochondrial genome of polled yak (Bos grunniens).

作者信息

Chu Min, Wu Xiaoyun, Liang Chunnian, Pei Jie, Ding Xuezhi, Guo Xian, Bao Pengjia, Yan Ping

机构信息

a Key Laboratory for Yak Breeding Engineering , Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Science , Lanzhou , P.R. China.

出版信息

Mitochondrial DNA A DNA Mapp Seq Anal. 2016 May;27(3):2032-3. doi: 10.3109/19401736.2014.974175. Epub 2014 Oct 27.

Abstract

Generally speaking, the hornless trait is also known as polled. Although the POLL locus could be assigned to a 1.36-Mb interval in the centromeric region of BTA1 (Georges et al., 1993; Drögemüller et al., 2005)), and (Liu et al., 2014) reported a 147-kb segment that included three protein-coding genes was the most likely location of the POLL mutation in domestic yaks, the underlying genetic basis for the polled trait is still unknown. In this work, the complete mitochondrial genome sequence of polled yak was determined for the first time. The total length of the mitogenome is 16,324 bp long, with the base composition of 33.72% A, 27.25% T, 25.83% C, and 13.20% G. It contained 13 protein-coding genes, 22 tRNA genes, 2 rRNA genes and 1 non-coding region (D-loop region). The gene order of polled yak mitogenome is identical to that observed in most other vertebrates. The complete mitogenome sequence information of polled yak will provide useful data for further studies on protection of genetic resources and phylogenetic relationships within Bos grunniens.

摘要

一般来说,无角性状也被称为无角(polled)。尽管POLL基因座可被定位到牛1号染色体(BTA1)着丝粒区域的一个1.36兆碱基区间(Georges等人,1993年;Drögemüller等人,2005年),并且(Liu等人,2014年)报道一个包含三个蛋白质编码基因的147千碱基片段是家养牦牛中POLL突变最可能的位置,但无角性状的潜在遗传基础仍然未知。在这项工作中,首次测定了无角牦牛的完整线粒体基因组序列。该线粒体基因组全长16324碱基对,碱基组成为33.72%A、27.25%T、25.83%C和13.20%G。它包含13个蛋白质编码基因、22个tRNA基因、2个rRNA基因和1个非编码区(D环区)。无角牦牛线粒体基因组的基因排列顺序与大多数其他脊椎动物中观察到的相同。无角牦牛的完整线粒体基因组序列信息将为进一步研究牦牛遗传资源保护和系统发育关系提供有用的数据。

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