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野生牦牛(Bos mutus)线粒体基因组全序列的特征分析

Characterization of the complete mitochondrial genome sequence of wild yak (Bos mutus).

作者信息

Chunnian Liang, Wu Xiaoyun, Ding Xuezhi, Wang Hongbo, Guo Xian, Chu Min, Bao Pengjia, Yan Ping

机构信息

a Key Laboratory for Yak Breeding Engineering of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences , Lanzhou , China.

出版信息

Mitochondrial DNA A DNA Mapp Seq Anal. 2016 Nov;27(6):4266-4267. doi: 10.3109/19401736.2015.1060420. Epub 2016 May 20.

Abstract

Wild yak is a special breed in China and it is regarded as an important genetic resource for sustainably developing the animal husbandry in Tibetan area and enriching region's biodiversity. The complete mitochondrial genome of wild yak (16,322 bp in length) displayed 37 typical animal mitochondrial genes and A + T-rich (61.01%), with an overall G + C content of only 38.99%. It contained a non-coding control region (D-loop), 13 protein-coding genes, two rRNA genes, and 22 tRNA genes. Most of the genes have ATG initiation codons, whereas ND2, ND3, and ND5 genes start with ATA and were encoded on H-strand. The gene order of wild yak mitogenome is identical to that observed in most other vertebrates. The complete mitochondrial genome sequence of wild yak reported here could provide valuable information for developing genetic markers and phylogenetic analysis in yak.

摘要

野牦牛是中国的一个特殊品种,被视为可持续发展藏区畜牧业和丰富该地区生物多样性的重要遗传资源。野牦牛的完整线粒体基因组(长度为16,322 bp)包含37个典型的动物线粒体基因,富含A+T(61.01%),总体G+C含量仅为38.99%。它包含一个非编码控制区(D-loop)、13个蛋白质编码基因、两个rRNA基因和22个tRNA基因。大多数基因具有ATG起始密码子,而ND2、ND3和ND5基因以ATA起始,且在重链上编码。野牦牛线粒体基因组的基因顺序与大多数其他脊椎动物中观察到的相同。本文报道的野牦牛完整线粒体基因组序列可为牦牛遗传标记开发和系统发育分析提供有价值的信息。

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