Haga Nobuhiro, Ogawa Soichiro, Yabe Michihiro, Akaihata Hidenori, Hata Junya, Sato Yuichi, Ishibashi Kei, Hasegawa Osamu, Kikuchi Ken, Shishido Fumio, Kojima Yoshiyuki
1 Department of Urology, School of Medicine, Fukushima Medical University , Fukushima, Japan .
2 Department of Radiology, School of Medicine, Fukushima Medical University , Fukushima, Japan .
J Endourol. 2015 Jun;29(6):683-90. doi: 10.1089/end.2014.0708. Epub 2014 Dec 11.
The aim of the present study is to elucidate factors contributing to early recovery of urinary continence after robot-assisted laparoscopic radical prostatectomy (RARP) from the perspective of urethral and vesical anatomical features after RARP.
Sixty consecutive patients undergoing RARP also underwent pre- and postoperative urethrovesicography (UVG). Both pre- and postoperative UVG evaluated the posterior-urethral vesical angle and position of the urethrovesical junction. Postoperative UVG was performed 7 days after RARP and also evaluated postoperative membranous urethral length (MUL) and the postoperative degree of atony of the external urethral sphincter. Associations were analyzed between pre- or postoperative UVG variables and urinary incontinence as well as between UVG variables significantly correlating with urinary incontinence and neurovascular bundle-preservation procedures.
Postoperative MUL was the only factor significantly associated with the state of continence in the early postoperative period according to multivariate logistic regression analysis (odds ratio, 1.94; 95% confidence interval, 1.22-3.12; p<0.005). A cutoff value of 17 mm offered the best accuracy in receiver operating characteristics analysis. Postoperative MUL was significantly increased in the group with preservation of the neurovascular bundle (p=0.01).
Postoperative MUL is the most important factor for recovery of urinary continence in the early postoperative period after RARP. Postoperative MUL >17 mm as measured on UVG can be expected to predict early recovery of urinary continence. Postoperative MUL was greater with preservation of the neurovascular bundle, thus allowing early recovery of urinary continence.
本研究旨在从机器人辅助腹腔镜根治性前列腺切除术(RARP)后尿道和膀胱的解剖学特征角度,阐明有助于术后早期尿失禁恢复的因素。
连续60例行RARP的患者术前行尿道膀胱造影(UVG),术后也进行了UVG检查。术前和术后的UVG均评估后尿道膀胱角和尿道膀胱连接部的位置。术后UVG在RARP术后7天进行,还评估了术后膜部尿道长度(MUL)和尿道外括约肌的术后失弛缓程度。分析术前或术后UVG变量与尿失禁之间的关联,以及与尿失禁显著相关的UVG变量与神经血管束保留手术之间的关联。
根据多因素逻辑回归分析,术后MUL是术后早期与尿失禁状态显著相关的唯一因素(比值比,1.94;95%置信区间,1.22 - 3.12;p<0.005)。在受试者工作特征分析中,17毫米的截断值具有最佳准确性。保留神经血管束的组术后MUL显著增加(p = 0.01)。
术后MUL是RARP术后早期尿失禁恢复的最重要因素。UVG测量的术后MUL>17毫米有望预测尿失禁的早期恢复。保留神经血管束时术后MUL更大,从而使尿失禁得以早期恢复。