Oetoro Samuel, Makmun Lukman H, Lukito Widjaja, Wijaya Andi
Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Acta Med Indones. 2014 Jul;46(3):199-208.
to evaluate the effect of weight loss program on fat mass, visceral fat rating and metabolic syndrome markers in obese subjects with weight cycling.
this was an 8-week open trial. The subjects were recruited consecutively from Balai Kota DKI Jaya. Subjects were classified into two groups according to the fluctuation of weight gain (weight cycling/WC and first encounter obesity/FEO group). Both groups were assigned to receive weight loss program consisted with following goals: a 1000 kcal energy intake reduction and 45 minutes mild-to-moderate intensity physical activity three times a week. Body composition (fat mass, visceral fat rating), and metabolic syndrome markers (waist circumference and triglyceride levels) were measured at baseline, week 4 and at the end of study.
seventy two subjects completed the study (34 subjects in WC group and 38 subjects in FEO group). Following weight loss program, a decrease in fat mass, visceral fat rating, and waist circumference was lower in WC group compared with FEO group but it was not statistically significant (p>0.05). Triglyceride levels were decreased in the FEO group while it was increased in WC group. However the difference was not significant (p=0.055).
weight loss program may contribute to changes in body composition and metabolic syndrome markers in obese subjects, which the response appears to be worse in weight cyclers.
评估减肥计划对体重反复波动的肥胖受试者的脂肪量、内脏脂肪评级和代谢综合征标志物的影响。
这是一项为期8周的开放试验。受试者连续从雅加达特区市政府招募。根据体重增加的波动情况（体重反复波动/WC组和初发肥胖/FEO组）将受试者分为两组。两组均被安排接受减肥计划，目标如下：减少1000千卡能量摄入，每周进行三次45分钟的轻度至中度强度体育活动。在基线、第4周和研究结束时测量身体成分（脂肪量、内脏脂肪评级）和代谢综合征标志物（腰围和甘油三酯水平）。
72名受试者完成了研究（WC组34名受试者，FEO组38名受试者）。经过减肥计划后，WC组的脂肪量、内脏脂肪评级和腰围下降幅度低于FEO组，但差异无统计学意义（p>0.05）。FEO组的甘油三酯水平下降，而WC组则升高。然而，差异不显著（p=0.055）。
减肥计划可能有助于肥胖受试者身体成分和代谢综合征标志物的改变，体重反复波动者的反应似乎更差。
