Witjaksono Fiastuti, Jutamulia Joan, Annisa Nagita Gianty, Prasetya Septian Ika, Nurwidya Fariz
Department of Nutrition, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jl. Salemba Raya No. 6, Jakarta, 10430, Indonesia.
BMC Res Notes. 2018 Sep 21;11(1):674. doi: 10.1186/s13104-018-3781-z.
Many individuals with visceral obesity who previously had succeeded in reducing body weight regain and this loss-gain cycle repeats several times which is called as weight cycling. We aimed to evaluate the effect of a low calorie high protein diet (HP) compared to a low calorie standard protein diet (SP) on waist circumference of visceral obese adults with history of weight cycling.
In this open-randomized clinical trial, participants were asked to follow dietary plan with reduction in daily caloric intake ranging from 500 to 1000 kcal from usual daily amount with minimum daily amount of 1000 kcal for 8 weeks and were divided in two groups: HP group with protein as 22-30% total calorie intake; and SP group with protein as 12-20% total calorie intake. There was a statistically significant difference (P < 0.001) between waist circumference before and after the dietary intervention among both groups. Meanwhile, there was no statistically significant difference in the mean reduction of waist circumference between HP and SP groups (P = 0.073). Taken together, the protein proportion does not significantly affected waist circumference. Trial registration ClinicalTrials.gov NCT03374150, 11 December 2017.
许多曾成功减重的内脏型肥胖个体体重会反弹，这种减重-增重循环会反复出现多次，这被称为体重循环。我们旨在评估低热量高蛋白饮食（HP）与低热量标准蛋白饮食（SP）相比，对有体重循环史的内脏型肥胖成年人腰围的影响。
在这项开放随机临床试验中，要求参与者遵循饮食计划，将每日热量摄入量从通常的每日摄入量减少500至1000千卡，最低每日摄入量为1000千卡，持续8周，并分为两组：HP组，蛋白质占总热量摄入的22%-30%；SP组，蛋白质占总热量摄入的12%-20%。两组饮食干预前后的腰围存在统计学显著差异（P<0.001）。同时，HP组和SP组腰围平均减少量无统计学显著差异（P=0.073）。总体而言，蛋白质比例对腰围无显著影响。试验注册ClinicalTrials.gov NCT03374150，2017年12月11日。
