Flumeri E N, Caporale A, Giuliani A, Teneriello F, Marum M Y, Rivas Y
G E N. 1989 Oct-Dec;43(4):266-71.
The clinical aspects, surgical treatment and outcome of 16 consecutive patients treated for toxic megacolon secondary to ulcerative colitis at the 1st department of surgery at the university of Rome between 1976 and 1987 were reviewed. The surgical management consisted in total colectomy and immediate ileo-rectal anastomosis, without protective ileostomy in 14 patients and total colectomy with terminal ileostomy and ileorectal anastomosis in 2 patients, 5 months later. No postoperative mortality was observe the immediate complications were: anastomotic leakage, (one case) and rectal bleeding (three cases). The late complications were: ileo-anastomotic stump fistula and perforation (two cases). Protectomy, due to colitis recrudescence, in the rectal remnant 10 months after surgery. These results encourage the total colectomy with immediate ileorectal anastomosis for the treatment of toxic megacolon.
回顾了1976年至1987年间在罗马大学第一外科接受治疗的16例溃疡性结肠炎继发中毒性巨结肠患者的临床情况、手术治疗及结果。手术处理包括全结肠切除术及立即行回肠直肠吻合术,14例患者未行保护性回肠造口术,2例患者在5个月后行全结肠切除术、末端回肠造口术及回肠直肠吻合术。未观察到术后死亡,近期并发症有:吻合口漏(1例)和直肠出血(3例)。远期并发症有:回肠吻合口残端瘘和穿孔(2例)。术后10个月因结肠炎复发,对直肠残端行直肠切除术。这些结果支持采用全结肠切除术并立即行回肠直肠吻合术治疗中毒性巨结肠。