来自铁皮石斛的八种新联苄衍生物。
Eight new bibenzyl derivatives from Dendrobium candidum.
作者信息
Li Yan, Wang Chun-Lan, Zhao Hai-Jun, Guo Shun-Xing
机构信息
a Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100193 , China.
出版信息
J Asian Nat Prod Res. 2014;16(11):1035-43. doi: 10.1080/10286020.2014.967230. Epub 2014 Oct 30.
Eight bibenzyl derivatives, namely dendrocandins J-Q (1-8), were isolated from the stems of Dendrobium candidum. Their structures were elucidated by 1D and 2D NMR experiments and mass spectrometry. Compounds 1-8 were examined for antioxidant activity by 1,1-diphenyl-2-picrylhydrazyl free radical scavenging assay, and the IC50 values were 36.8, 70.2, 45.0, 60.5, 87.6, 50.4, 22.3, and 30.3 μM, respectively.
从铁皮石斛茎中分离出8种联苄衍生物，即石斛菌素J - Q（1 - 8）。通过一维和二维核磁共振实验及质谱对其结构进行了鉴定。采用1,1 - 二苯基 - 2 - 苦基肼自由基清除法对化合物1 - 8的抗氧化活性进行了检测，其半数抑制浓度（IC50）值分别为36.8、70.2、45.0、60.5、87.6、50.4、22.3和30.3μM。
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