Li Yetian, Wang Wei, Wang Guangye, Yin Zongsheng
Department of Orthopaedics, No. 2 People's Hospital Wuhu.
Department of Orthopaedics, The First Affiliated Hospital of Anhui Medical University Hefei 230032, China.
Int J Clin Exp Med. 2014 Sep 15;7(9):3118-25. eCollection 2014.
The study aimed to observe the complications after the bilateral internal iliac arteries and the median sacral artery embolization by different severity and combinations of gelfoam particles.
Sixteen healthy adult dogs were randomly divided into five groups. Under the monitoring of digital subtraction angiography (DSA), gelfoam particles with diameter of 50-150 μm were applied. In group A, embolization was performed up to the trunk of bilateral internal iliac arteries and the median sacral artery; in group B, embolization was up to the trunk of bilateral internal iliac arteries; in group C, embolization was up to the first branch of bilateral internal iliac arteries and the median sacral artery; in group D, embolization was up to the trunk of unilateral internal iliac artery and the median sacral artery; in group E embolization was performed up to the trunk of unilateral internal iliac artery.
Seven dogs died within 48 hours after embolization. In the dead animals of groups A, C and D, there were rectum necrosis and lamellar obfuscation and hemorrhage edema in bladder. In the histological examination, there are rectum and bladder cell dissociation, inflammatory cell infiltration and epithelial cell ablating in the dead animals. The embolization mainly presented in arterioles with a diameter of 100-200 μm.
When gelfoam particles of 50-150 μm in diameter were applied for embolization in the internal iliac artery and median sacral artery, at least unilateral internal iliac artery should be preserved when embolization is performed in the proximal artery and the trunk.
本研究旨在观察不同大小及组合的明胶海绵颗粒栓塞双侧髂内动脉及骶中动脉后的并发症。
16只健康成年犬随机分为5组。在数字减影血管造影（DSA）监测下，应用直径为50 - 150μm的明胶海绵颗粒。A组栓塞至双侧髂内动脉主干及骶中动脉；B组栓塞至双侧髂内动脉主干；C组栓塞至双侧髂内动脉第一分支及骶中动脉；D组栓塞至单侧髂内动脉主干及骶中动脉；E组栓塞至单侧髂内动脉主干。
7只犬在栓塞后48小时内死亡。A、C和D组死亡动物出现直肠坏死，膀胱片状模糊及出血水肿。组织学检查显示，死亡动物直肠和膀胱细胞解离、炎性细胞浸润及上皮细胞脱落。栓塞主要发生在直径为100 - 200μm的小动脉。
当应用直径50 - 150μm的明胶海绵颗粒栓塞髂内动脉及骶中动脉时，在近端动脉及主干进行栓塞时至少应保留一侧髂内动脉。
