Weber R S, Palmer J M, el-Naggar A, McNeese M D, Guillamondegui O M, Byers R M
Department of Head and Neck Surgery, University of Texas M.D. Anderson Cancer Center, Houston 77030.
Laryngoscope. 1989 Jan;99(1):6-9. doi: 10.1288/00005537-198901000-00002.
Between 1944 and 1985, 50 patients with minor salivary gland tumors of the lip and buccal mucosa were treated at M.D. Anderson Cancer Center: 19 with lip and 31 with buccal mucosa tumors. The male-to-female ratios were 2.8:1 for lip and 1:2.9 for the buccal mucosa tumors. Patient age at presentation ranged from 18 to 98 years with a median of 55 years. Treatment consisted of surgery alone for 28 patients, radiotherapy in 9 patients, and combined therapy for 13. Adenoid cystic carcinoma was the predominant histologic type, accounting for 21 (42%) tumors. Risk for recurrence was influenced by histology, the presence of perineural invasion, and the location of the primary tumor. Six patients developed recurrent disease; all six had adenoid cystic carcinoma. The therapeutic approach and the rationale for combined treatment of these neoplasms are discussed.
1944年至1985年间，50例唇部和颊黏膜小唾液腺肿瘤患者在MD安德森癌症中心接受了治疗：19例唇部肿瘤患者和31例颊黏膜肿瘤患者。唇部肿瘤患者的男女比例为2.8:1，颊黏膜肿瘤患者的男女比例为1:2.9。患者就诊时的年龄范围为18岁至98岁，中位数为55岁。28例患者仅接受手术治疗，9例接受放射治疗，13例接受联合治疗。腺样囊性癌是主要的组织学类型，占21例（42%）肿瘤。复发风险受组织学、神经周围浸润情况和原发肿瘤位置的影响。6例患者出现复发性疾病；所有6例均为腺样囊性癌。本文讨论了这些肿瘤的治疗方法以及联合治疗的原理。
