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高血压:孟加拉国农村地区的治疗依从性——一项基于人群研究的结果

Hypertension: adherence to treatment in rural Bangladesh--findings from a population-based study.

作者信息

Khanam Masuma Akter, Lindeboom Wietze, Koehlmoos Tracey Lynn Perez, Alam Dewan Shamsul, Niessen Louis, Milton Abul Hasnat

机构信息

Centre for Control of Chronic Diseases in Bangladesh, icddr,b, Mohakali, Bangladesh; Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, Faculty of Health and Medicine, The University of Newcastle, Callaghan, NSW, Australia.

Centre for Control of Chronic Diseases in Bangladesh, icddr,b, Mohakali, Bangladesh.

出版信息

Glob Health Action. 2014 Oct 20;7:25028. doi: 10.3402/gha.v7.25028. eCollection 2014.

Abstract

BACKGROUND

Poor adherence has been identified as the main cause of failure to control hypertension. Poor adherence to antihypertensive treatment is a significant cardiovascular risk factor, which often remains unrecognized. There are no previous studies that examined adherence with antihypertensive medication or the characteristics of the non-adherent patients in Bangladesh.

OBJECTIVE

This paper aims to describe hypertension and factors affecting adherence to treatment among hypertensive persons in rural Bangladesh.

DESIGN

The study population included 29,960 men and women aged 25 years and older from three rural demographic surveillance sites of the International Center for Diarrheal Disease Research, Bangladesh (icddr,b): Matlab, Abhoynagar, and Mirsarai. Data was collected by a cross-sectional design on diagnostic provider, initial, and current treatment. Discontinuation of medication at the time of interview was defined as non-adherence to treatment.

RESULTS

The prevalence of hypertension was 13.67%. Qualified providers diagnosed only 53.5% of the hypertension (MBBS doctors 46.1 and specialized doctors 7.4%). Among the unqualified providers, village doctors diagnosed 40.7%, and others (nurse, health worker, paramedic, homeopath, spiritual healer, and pharmacy man) each diagnosed less than 5%. Of those who started treatment upon being diagnosed with hypertension, 26% discontinued the use of medication. Age, sex, education, wealth, and type of provider were independently associated with non-adherence to medication. More men discontinued the treatment than women (odds ratio [OR] 1.74, confidence interval [CI] 1.48-2.04). Non-adherence was greater when hypertension was diagnosed by unqualified providers (OR 1.52, CI 1.31-1.77). Hypertensive patients of older age, least poor quintile, and higher education were less likely to be non-adherent. Patients with cardiovascular comorbidity were also less likely to be non-adherent to antihypertensive medication (OR 0.79, CI 0.64-0.97).

CONCLUSIONS

Although village doctors diagnose 40% of hypertension, their treatments are associated with a higher rate of non-adherence to medication. The hypertension care practices of the village doctors should be explored by additional research. More emphasis should be placed on men, young people, and people with low education. Health programs focused on education regarding the importance of taking continuous antihypertensive medication is now of utmost importance.

摘要

背景

依从性差已被确定为高血压控制不佳的主要原因。抗高血压治疗依从性差是一个重要的心血管危险因素,往往未被认识到。以前没有研究调查过孟加拉国抗高血压药物的依从性或不依从患者的特征。

目的

本文旨在描述孟加拉国农村高血压患者的高血压情况及影响治疗依从性的因素。

设计

研究人群包括来自孟加拉国腹泻病研究国际中心(icddr,b)的三个农村人口监测点的29960名年龄在25岁及以上的男性和女性:Matlab、Abhoynagar和Mirsarai。通过横断面设计收集有关诊断提供者、初始治疗和当前治疗的数据。访谈时停药被定义为治疗不依从。

结果

高血压患病率为13.67%。合格的提供者仅诊断出53.5%的高血压患者(医学学士医生诊断出46.1%,专科医生诊断出7.4%)。在不合格的提供者中,乡村医生诊断出40.7%,其他人员(护士、卫生工作者、护理人员、顺势疗法医生、精神治疗师和药剂师)每人诊断出的比例均低于5%。在被诊断为高血压后开始治疗的患者中,26%停止了用药。年龄、性别、教育程度、财富和提供者类型与药物治疗不依从独立相关。停止治疗的男性多于女性(比值比[OR]为1.74,置信区间[CI]为1.48 - 2.04)。由不合格提供者诊断出高血压时,不依从性更高(OR为1.52,CI为1.31 - 1.77)。年龄较大、最不贫困五分位数和受过高等教育的高血压患者不太可能不依从。患有心血管合并症的患者也不太可能不依从抗高血压药物治疗(OR为0.79,CI为0.64 - 0.97)。

结论

尽管乡村医生诊断出40%的高血压患者,但其治疗与更高的药物治疗不依从率相关。应通过进一步研究探讨乡村医生的高血压护理实践。应更多地关注男性、年轻人和低教育程度人群。现在,专注于教育人们认识持续服用抗高血压药物重要性的健康项目至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6137/4212079/126cdbaf5658/GHA-7-25028-g001.jpg

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