School of Medicine, Stanford University, Stanford, USA.
BMC Public Health. 2012 Jun 13;12:434. doi: 10.1186/1471-2458-12-434.
Belief is that chronic disease prevalence is rising in Bangladesh since death from them has increased. We reviewed published cardiovascular (CVD) and Type 2 Diabetes Mellitus (T2DM) studies between 1995 and 2010 and conducted a meta-analysis of disease prevalence.
A systematic search of CVD and T2DM studies yielded 29 eligible studies (outcome: CVD only = 12, T2DM only = 9, both = 8). Hypertension (HTN) was the primary outcome of CVD studies. HTN and T2DM were defined with objective measures and standard cut-off values. We assessed the study quality based on sampling frame, sample size, and disease evaluation. Random effects models calculated pooled disease prevalence (95% confidence interval) in studies with general population samples (n = 22).
The pooled HTN and T2DM prevalence were 13.7% (12.1%-15.3%) and 6.7% (4.9%-8.6%), respectively. Both diseases exhibited a secular trend by 5-year intervals between 1995 and 2010 (HTN = 11.0%, 12.8%, 15.3%, T2DM = 3.8%, 5.3%, 9.0%). HTN was higher in females (M vs. F: 12.8% vs.16.1%) but T2DM was higher in males (M vs. F: 7.0% vs. 6.2%) (non-significant). Both HTN and T2DM were higher in urban areas (urban vs. rural: 22.2% vs. 14.3% and 10.2% vs. 5.1% respectively) (non-significant). HTN was higher among elderly and among working professionals. Both HTN and T2DM were higher in 'high- quality' studies.
There is evidence of a rising secular trend of HTN and T2DM prevalence in Bangladesh. Future research should focus on the evolving root causes, incidence, and prognosis of HTN and T2DM.
据信，自孟加拉国因慢性病死亡人数增加以来，慢性病的患病率一直在上升。我们回顾了 1995 年至 2010 年期间发表的心血管疾病（CVD）和 2 型糖尿病（T2DM）研究，并对疾病患病率进行了荟萃分析。
对 CVD 和 T2DM 研究进行系统检索，得到 29 项合格研究（结局：仅 CVD = 12 项，仅 T2DM = 9 项，两者均有 = 8 项）。高血压（HTN）是 CVD 研究的主要结局。HTN 和 T2DM 采用客观测量和标准截断值进行定义。我们根据抽样框架、样本量和疾病评估来评估研究质量。使用具有一般人群样本的研究（n = 22）的随机效应模型计算了汇总疾病患病率（95%置信区间）。
汇总的 HTN 和 T2DM 患病率分别为 13.7%（12.1%-15.3%）和 6.7%（4.9%-8.6%）。1995 年至 2010 年期间，每 5 年的 HTN 和 T2DM 患病率均呈明显的时间趋势（HTN = 11.0%、12.8%、15.3%，T2DM = 3.8%、5.3%、9.0%）。女性 HTN 患病率较高（M 与 F：12.8%比 16.1%），而男性 T2DM 患病率较高（M 与 F：7.0%比 6.2%）（无统计学意义）。HTN 和 T2DM 均在城市地区较高（城市比农村：22.2%比 14.3%和 10.2%比 5.1%）（无统计学意义）。老年人群和职业人群中 HTN 患病率较高。HTN 和 T2DM 在“高质量”研究中更高。
有证据表明，孟加拉国 HTN 和 T2DM 的患病率呈上升趋势。未来的研究应重点关注 HTN 和 T2DM 的发病原因、发病率和预后的变化。
