Dutta Sourabh, Ganesh Meenakshi, Ray Pallab, Narang Anil
Departments of Pediatrics and *Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. Correspondence to: Dr Sourabh Dutta, Additional Professor, Division of Neonatology, Department of Pediatrics, PGIMER, Chandigarh 160 012, India.
Indian Pediatr. 2014 Oct;51(10):807-9. doi: 10.1007/s13312-014-0507-8.
To study intestinal colonization patterns in very low birth weight infants in the first week of life in a neonatal intensive care unit.
Meconium/stool specimens were obtained on days 1, 3, 5 and 7 from 38 very low-birth-weight infants in a level III neonatal intensive care unit.
On day 1, 45% had sterile guts, and by day 3, all infants were colonized. E. coli, K. pneumoniae and Enterococcus fecalis were predominant organisms. Lactobacilli was found in one isolate and Bifidobacteria was not detected during the study period. There was an association between formula feeding and E. coli colonization.
Very low birth weight infants admitted in neonatal intensive care units have abnormal intestinal colonization patterns.
研究新生儿重症监护病房中极低出生体重儿出生后第一周的肠道定植模式。
从一家三级新生儿重症监护病房的38名极低出生体重儿身上，在出生第1、3、5和7天采集胎粪/粪便标本。
第1天，45%的婴儿肠道无菌，到第3天，所有婴儿都被定植。大肠杆菌、肺炎克雷伯菌和粪肠球菌是主要的定植菌。在研究期间，仅在一份分离物中发现了乳酸杆菌，未检测到双歧杆菌。配方奶喂养与大肠杆菌定植之间存在关联。
入住新生儿重症监护病房的极低出生体重儿具有异常的肠道定植模式。
