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在实践中践行“神经”:转化研究、黏附与孔隙度的前景。

Enacting the 'neuro' in practice: translational research, adhesion and the promise of porosity.

作者信息

Brosnan Caragh, Michael Mike

出版信息

Soc Stud Sci. 2014 Oct;44(5):680-700. doi: 10.1177/0306312714534333.

Abstract

This article attends to the processes through which neuroscience and the neuro are enacted in a specific context: a translational neuroscience research group that was the setting of an ethnographic study. The article therefore provides a close-up perspective on the intersection of neuroscience and translational research. In the scientific setting we studied, the neuro was multiple and irreducible to any particular entity or set of practices across a laboratory and clinical divide. Despite this multiplicity, the group's work was held together through the 'promise of porosity'--that one day there would be translation of lab findings into clinically effective intervention. This promise was embodied in the figure of the Group Leader whose expertise spanned clinical and basic neurosciences. This is theorized in terms of a contrast between cohesion and adhesion in interdisciplinary groupings. We end by speculating on the role of 'vivification'--in our case mediated by the Group Leader--in rendering 'alive' the expectations of interdisciplinary collaboration.

摘要

本文关注神经科学以及“神经”在特定背景下得以确立的过程:一个转化神经科学研究小组,该小组是一项人种志研究的场所。因此,本文提供了一个关于神经科学与转化研究交叉领域的特写视角。在我们研究的科学环境中,“神经”具有多重性,无法简化为跨越实验室与临床界限的任何特定实体或实践集合。尽管存在这种多重性,但该小组的工作通过“孔隙度的承诺”凝聚在一起——即有朝一日实验室的研究成果将转化为临床有效的干预措施。这一承诺体现在组长这一人物身上,其专业知识涵盖临床和基础神经科学。这是根据跨学科团队中凝聚与黏附之间的对比进行理论阐述的。我们最后推测“赋予活力”(在我们的案例中由组长介导)在使跨学科合作的期望“鲜活起来”方面所起的作用。

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