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血液、肉类与规模化组织工程:生物医学和农业食品领域的前景、预期市场及性能表现

Blood, meat, and upscaling tissue engineering: Promises, anticipated markets, and performativity in the biomedical and agri-food sectors.

作者信息

Stephens Neil, King Emma, Lyall Catherine

机构信息

Social Sciences and Communications, Brunel University London, Kingston Lane, Uxbridge, Middlesex 01895268460, UK.

University of Stirling, Stirling, UK.

出版信息

Biosocieties. 2018 Jun;13:368-388. doi: 10.1057/s41292-017-0072-1. Epub 2018 Jan 15.

DOI:10.1057/s41292-017-0072-1
PMID:34249140
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7611148/
Abstract

Tissue engineering is a set of biomedical technologies, including stem cell science, which seek to grow biological tissue for a diversity of applications. In this paper, we explore two emergent tissue engineering technologies that seek to cause a step change in the upscaling capacity of cell growth: cultured blood and cultured meat. Cultured blood technology seeks to replace blood transfusion with a safe and affordable bioengineered replacement. Cultured meat technology seeks to replace livestock-based food production with meat produced in a bioreactor. Importantly, cultured meat technology straddles the industrial contexts of biomedicine and agrifood. In this paper, we articulate (i) the shared and divergent promissory trajectories of the two technologies and (ii) the anticipated market, consumer, and regulatory contexts of each. Our analysis concludes by discussing how the sectoral ontologies of biomedicine and agri-food impact the performative capacity of each technology's promissory trajectory.

摘要

组织工程是一系列生物医学技术,包括干细胞科学,旨在培育用于多种应用的生物组织。在本文中,我们探讨了两种新兴的组织工程技术,它们试图在扩大细胞生长能力方面带来跨越式变化:培养血液和培养肉。培养血液技术旨在用安全且经济实惠的生物工程替代品取代输血。培养肉技术旨在用生物反应器中生产的肉类取代基于牲畜的食品生产。重要的是,培养肉技术跨越了生物医学和农业食品的产业背景。在本文中,我们阐述了(i)这两种技术共同和不同的预期发展轨迹,以及(ii)每种技术预期的市场、消费者和监管背景。我们的分析最后讨论了生物医学和农业食品的部门本体如何影响每种技术预期发展轨迹的实践能力。

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本文引用的文献

1
What's in a name: are cultured red blood cells 'natural'?名称有何含义:培养的红细胞是“天然的”吗?
Sociol Health Illn. 2018 May;40(4):687-701. doi: 10.1111/1467-9566.12717. Epub 2018 Mar 2.
2
Benevolent technotopias and hitherto unimaginable meats: Tracing the promises of in vitro meat.仁慈的技术乌托邦与前所未有的肉类:探寻体外培养肉的前景。
Soc Stud Sci. 2016 Oct;46(5):725-748. doi: 10.1177/0306312716658561. Epub 2016 Aug 20.
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Doing laboratory ethnography: reflections on method in scientific workplaces.开展实验室人种志研究:对科研工作场所方法的思考
Qual Res. 2017 Apr;17(2):202-216. doi: 10.1177/1468794116678040. Epub 2017 Apr 13.
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Haematopoietic stem and progenitor cells from human pluripotent stem cells.源自人类多能干细胞的造血干细胞和祖细胞。
Nature. 2017 May 25;545(7655):432-438. doi: 10.1038/nature22370. Epub 2017 May 17.
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Conversion of adult endothelium to immunocompetent haematopoietic stem cells.成年内皮细胞向具有免疫活性的造血干细胞的转化。
Nature. 2017 May 25;545(7655):439-445. doi: 10.1038/nature22326. Epub 2017 May 17.
6
Attitudes to in vitro meat: A survey of potential consumers in the United States.对体外培养肉的态度:美国潜在消费者调查
PLoS One. 2017 Feb 16;12(2):e0171904. doi: 10.1371/journal.pone.0171904. eCollection 2017.
7
Explicit and implicit attitude toward an emerging food technology: The case of cultured meat.对一种新兴食品技术的显性和隐性态度: cultured meat的案例。 (注:“cultured meat”常见释义为“实验室培育肉”“人造肉”等 )
Appetite. 2017 Jan 1;108:245-254. doi: 10.1016/j.appet.2016.10.002. Epub 2016 Oct 4.
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Promise and Ontological Ambiguity in the Meat Imagescape: From Laboratory Myotubes to the Cultured Burger.肉类图景中的前景与本体论模糊性:从实验室肌管到人造肉饼
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Using qualitative research methods in biomedical innovation: the case of cultured red blood cells for transfusion.在生物医学创新中运用定性研究方法:以用于输血的培养红细胞为例。
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The first bite: Imaginaries, promotional publics and the laboratory grown burger.第一口:想象、宣传受众与实验室培育汉堡
Public Underst Sci. 2017 Feb;26(2):148-163. doi: 10.1177/0963662516639001. Epub 2016 Aug 2.