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生物膜的热效应与敏感性

Thermal effects and sensitivity of biological membranes.

作者信息

Islas León D

机构信息

Department of Physiology, School of Medicine, National Autonomous University of Mexico (UNAM), Mexico City, Mexico.

出版信息

Curr Top Membr. 2014;74:1-17. doi: 10.1016/B978-0-12-800181-3.00001-4.

DOI:10.1016/B978-0-12-800181-3.00001-4
PMID:25366231
Abstract

Temperature is one of the key parameters that controlled the origin and evolution of life on earth and it continues to be a principal regulator of the functions of organisms. Some aspects of the response of simple and complex organisms to temperature variations are encoded in the physical properties of the cell components, with the all-important plasma membrane playing a principal role. Other responses to temperature are more specific and through evolution, specialized receptors with particular temperature sensitivities have appeared to mediate this signaling. While some of these receptors are ancient and can be found in very primitive organisms, it seems that the mechanisms used by prokaryotes and eukaryotes are very different, indicating that temperature sensitivity has evolved in more than one occasion during evolution.

摘要

温度是控制地球上生命起源和演化的关键参数之一,并且它仍然是生物体功能的主要调节因子。简单和复杂生物体对温度变化的反应的某些方面编码在细胞成分的物理特性中,其中至关重要的质膜起着主要作用。对温度的其他反应则更为特异,并且通过进化,具有特定温度敏感性的专门受体似乎已出现来介导这种信号传导。虽然其中一些受体很古老,并且可以在非常原始的生物体中找到,但原核生物和真核生物所使用的机制似乎非常不同,这表明温度敏感性在进化过程中不止一次地发生了演化。

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