Zätterström Ulf, Boysen Morten, Evensen Jan Folkvard
Department of Oto-rhino-laryngology, Head and Neck Surgery, Oslo University Hospital (OUS), Radiumhospitalet, Oslo, Norway
Department of Oto-rhino-laryngology, Head and Neck Surgery, Oslo University Hospital (OUS), Radiumhospitalet, Oslo, Norway.
Anticancer Res. 2014 Nov;34(11):6593-9.
There is little evidence to prove that frequent out-patient consultations lead to better prognosis in patients treated for oral squamous cell carcinoma. Furthermore, there is no consensus regarding the timing and number of follow-up consultations or the duration of monitoring after completed therapy.
We prospectively recorded demographic and clinical data of 537 patients treated over a period of 15 years with complete follow-up of 18 years in a tertiary academic Center.
Out of 537 patients considered free of disease after treatment, 196 (36%) developed recurrent disease during follow-up. Self-reported symptoms led to diagnosis of the recurrence in 78% of the cases. Only 22% of recurrences were detected through physical examination of asymptomatic patients. There was no difference in disease-free survival in-between these two groups.
Follow-up routines are indispensable as part of cancer treatment but can be more cost-efficient when patients are educated and encouraged to report subjective symptoms. Trained personnel in collaboration with head and neck specialists can handle parts of follow-up routines.
几乎没有证据表明,对于接受口腔鳞状细胞癌治疗的患者而言,频繁的门诊会诊能带来更好的预后。此外,对于随访会诊的时间、次数或完成治疗后的监测时长,目前尚无共识。
我们前瞻性地记录了一家三级学术中心15年间治疗的537例患者的人口统计学和临床数据,并进行了长达18年的完整随访。
在537例治疗后被认为无疾病的患者中,196例(36%)在随访期间出现疾病复发。自我报告的症状导致78%的病例诊断出复发。只有22%的复发是通过对无症状患者的体格检查发现的。这两组患者的无病生存期没有差异。
随访程序作为癌症治疗的一部分是必不可少的,但当患者接受教育并被鼓励报告主观症状时,随访程序可能更具成本效益。经过培训的人员与头颈专科医生协作,可以处理部分随访程序。