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[肉桂油对所选革兰氏阳性菌和革兰氏阴性菌的抗菌活性]

[The antibacterial activity of cinnamon oil on the selected gram-positive and gram-negative bacteria].

作者信息

Urbaniak Anna, Głowacka Anna, Kowalczyk Edward, Lysakowska Monika, Sienkiewicz Monika

出版信息

Med Dosw Mikrobiol. 2014;66(2):131-41.

Abstract

INTRODUCTION

The aim of our study was to determine the antibacterial activity of cinnamon bark oil against Gram-positive and Gram-negative isolates belonging to Staphylococcus, Enterococcus, Enterobacter and Acinetobacter genera come from different clinical specimens.

METHODS

The microdilution method was used to determine the minimum inhibitory concentration--MIC for cinnamon bark oil. Susceptibility testing to antibiotics was carried out using disc-diffusion method.

RESULTS

Our investigations showed that the tested cinnamon bark oil was inhibiting activity against all isolates. The MIC for Gram-positive bacteria were between 01.25 and 1.5 μl/ml and for Gram-negative between 1.0 and 1.75 μl/ml. The tested bacteria come from Staphylococcus, Enterococcus, Enterobacter and Acinetobacter genera were susceptible to essential oil obtained from Cinnamomum zeylanicum Ness in low concentrations, despite the fact that the bacteria characterized the high resistance to recommended antibiotics. No correlation was found between the antibiotic resistance of the bacterial strains and their sensitivity to essential oil.

CONCLUSIONS

The cinnamon bark oil due to the strong activity can be used as alternative antibacterial agents in cosmetics, toiletries and disinfectants applied in hospital environment.

摘要

引言

我们研究的目的是确定肉桂皮油对来自不同临床标本的葡萄球菌属、肠球菌属、肠杆菌属和不动杆菌属的革兰氏阳性和革兰氏阴性分离株的抗菌活性。

方法

采用微量稀释法测定肉桂皮油的最低抑菌浓度(MIC)。使用纸片扩散法进行抗生素敏感性试验。

结果

我们的研究表明,受试肉桂皮油对所有分离株均有抑制活性。革兰氏阳性菌的MIC在01.25至1.5微升/毫升之间,革兰氏阴性菌的MIC在1.0至1.75微升/毫升之间。来自葡萄球菌属、肠球菌属、肠杆菌属和不动杆菌属的受试细菌对从锡兰肉桂中提取的精油低浓度敏感,尽管这些细菌对推荐抗生素具有高抗性。未发现菌株的抗生素抗性与其对精油的敏感性之间存在相关性。

结论

由于肉桂皮油具有较强的活性,可作为医院环境中化妆品、洗漱用品和消毒剂的替代抗菌剂。

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