Zhu Jian-Wei, Lu Zhong-Fa, Zheng Min
Department of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, No.88 Jiefang Rd, Hangzhou, China 310009.
Cutis. 2014 Oct;94(4):203-5.
Keratosis pilaris (KP) is a common inherited disorder characterized by small folliculocentric keratotic papules that may have surrounding erythema, which gives the skin a stippled appearance resembling gooseflesh. The extensor surfaces of the upper arms, thighs, and buttocks commonly are affected, but a generalized presentation may occur. We report the case of a 29-year-old woman with unilateral generalized KP in the second month of her second pregnancy. Both a genetic mutation and pregnancy-induced hormonal changes played possible roles in the development and progress of unilateral generalized KP in this patient.
毛发角化病（KP）是一种常见的遗传性疾病，其特征为以毛囊为中心的小角化性丘疹，周围可能有红斑，使皮肤呈现出类似鸡皮疙瘩的点状外观。上臂、大腿和臀部的伸侧表面通常会受到影响，但也可能出现全身性表现。我们报告了一例29岁女性患者，在其第二次怀孕的第二个月出现单侧全身性KP。基因突变和妊娠引起的激素变化可能在该患者单侧全身性KP的发生和发展中起了作用。
