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伴有黏蛋白沉积的红色毛发角化病。

Keratosis pilaris rubra with mucin deposition.

作者信息

Hosking Anna-Marie, Elsensohn Ashley, Makdisi Joy, Grando Sergei, de Feraudy Sebastien

机构信息

Department of Dermatology, University of California Irvine, Irvine, California.

出版信息

J Cutan Pathol. 2018 Dec;45(12):958-961. doi: 10.1111/cup.13365. Epub 2018 Oct 21.

Abstract

Keratosis pilaris (KP) is a benign cutaneous disorder characterized by folliculocentric hyperkeratotic papules most often occurring on the proximal extremities. Erythema is usually limited to perifollicular skin, but when keratosis pilaris presents on a background of confluent erythema, the term keratosis pilaris rubra (KPR) is used. The histological findings associated with KP have not been well described in the literature. Herein, we present a case of a 14-year-old male with a 7-year history of erythema and follicular-based papules over his bilateral cheeks, consistent with KPR. Histological examination revealed abundant mucin, keratotic follicular plugging, and periadnexal lymphocytosis. Our novel finding of abundant dermal mucin expands the histopathologic description of KPR.

摘要

毛发角化病(KP)是一种良性皮肤疾病,其特征为毛囊中心性角化过度丘疹,最常出现在四肢近端。红斑通常局限于毛囊周围皮肤,但当毛发角化病出现在融合性红斑背景上时,则使用毛发红糠疹(KPR)这一术语。与KP相关的组织学表现尚未在文献中得到充分描述。在此,我们报告一例14岁男性,双侧脸颊有7年红斑和毛囊性丘疹病史,符合KPR。组织学检查显示有大量黏蛋白、角化性毛囊堵塞和附件周围淋巴细胞浸润。我们发现大量真皮黏蛋白这一新颖发现扩展了KPR的组织病理学描述。

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