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多次小肠切除术后Peutz-Jeghers综合征患者通过手术和内镜下息肉切除术清除息肉

Polyp Clearance via Operative and Endoscopic Polypectomy in Patients With Peutz-Jeghers Syndrome After Multiple Small Bowel Resections.

作者信息

Lee Do Hyun, Shin Hyun Deok, Cho Woo Hee, Shin Kyoung Hwang, Lee Sora, Shin Jeong Eun, Namgung Hwan, Gwon Ji Eun

机构信息

Department of Internal Medicine, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea.

Department of Surgery, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea.

出版信息

Intest Res. 2014 Oct;12(4):320-7. doi: 10.5217/ir.2014.12.4.320. Epub 2014 Oct 27.

DOI:10.5217/ir.2014.12.4.320
PMID:25374499
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4214960/
Abstract

Peutz-Jeghers syndrome is an autosomal dominant inherited disease that manifests as a combination of mucocutaneous pigmentation and gastrointestinal hamartomatous polyps that usually cause intussusception and intestinal hemorrhage. We report the case of a 40-year-old male patient who was diagnosed 20 years ago and had previously undergone 3 intestinal resection surgeries. This time, with the use of combined operative and endoscopic polypectomy, more than 100 polyps were removed. This technique is useful for providing a "clean" small intestine that allows the patient a long interval between laparotomies and reduces the complications associated with multiple laparotomies and resections.

摘要

黑斑息肉综合征是一种常染色体显性遗传病，表现为皮肤黏膜色素沉着和胃肠道错构瘤性息肉，常导致肠套叠和肠道出血。我们报告一例40岁男性患者，20年前被诊断为此病，此前已接受过3次肠道切除手术。此次，通过联合手术和内镜下息肉切除术，切除了100多个息肉。该技术有助于提供一段“清洁”的小肠，使患者两次剖腹手术间隔时间延长，并减少与多次剖腹手术和切除术相关的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ecb/4214960/91eebda2ab27/ir-12-320-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ecb/4214960/e95ef2f9508b/ir-12-320-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ecb/4214960/a935a7bc3cdc/ir-12-320-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ecb/4214960/d5e38c6534ba/ir-12-320-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ecb/4214960/594141be9e8e/ir-12-320-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ecb/4214960/2c97a61ca9fb/ir-12-320-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ecb/4214960/91eebda2ab27/ir-12-320-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ecb/4214960/e95ef2f9508b/ir-12-320-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ecb/4214960/a935a7bc3cdc/ir-12-320-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ecb/4214960/d5e38c6534ba/ir-12-320-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ecb/4214960/594141be9e8e/ir-12-320-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ecb/4214960/2c97a61ca9fb/ir-12-320-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ecb/4214960/91eebda2ab27/ir-12-320-g006.jpg

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Small bowel intussusception caused by a jejunal polyp in Peutz-Jeghers syndrome: a case treated with double balloon enteroscopy.
黑斑息肉综合征中由空肠息肉引起的小肠套叠：一例经双气囊小肠镜治疗的病例
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Gut. 2010 Jul;59(7):975-86. doi: 10.1136/gut.2009.198499.
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LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis.间充质细胞中的LKB1信号传导是抑制胃肠道息肉形成所必需的。
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