Shanley Leticia A, Lin Hua, Flores Glenn
Division of General Pediatrics, University of Texas Southwestern Medical Center and Children's Medical Center , Dallas, TX , USA.
J Asthma. 2015 Jun;52(5):471-7. doi: 10.3109/02770903.2014.984843. Epub 2014 Nov 21.
Asthma is a leading cause of pediatric hospitalizations, but little is known about factors associated with length of stay (LOS) for asthma hospitalizations. The aim of this study was to identify factors associated with LOS for pediatric asthma hospitalizations.
The Pediatric Health Information System (PHIS) was used to cohort patients 2-17 years old with a primary asthma diagnosis discharged from 42 PHIS hospitals in 2011. Sociodemographic, temporal and health-status factors were examined. Bivariate and generalized-estimating-equation logistic regression analyses were performed to identify factors associated with LOS, after adjusting for severity of illness (SOI).
In total, 25,900 children were hospitalized, with a mean LOS of 1.9 days. In bivariate analysis, mean LOS was longer (p < 0.01) for patients with complex chronic conditions (CCC) (3.1 days versus 1.8 for non-CCC) and adolescents (2.3 versus 1.8 for 2-5 years old). In multivariable analysis, obstructive sleep apnea (OSA; OR 2.3; 95% CI: 1.8-2.9), older age (OR 1.3; 95% CI: 1.2-1.4), obesity (OR 1.3; 95% CI: 1.1-1.4), CCC (OR 1.3; 95% CI: 1.1-1.4), winter admissions (OR 1.2; 95% CI: 1.1-1.4), female gender (OR 1.1; 95% CI: 1.1-1.3), and weekend admissions (OR 1.1; 95% CI: 1.03-1.2) had higher odds of asthma LOS >2 days.
OSA, older age, obesity, CCC, winter and weekend admissions, and female gender are associated with longer LOS for pediatric asthma hospitalizations, after adjustment for SOI. The study findings suggest that interventions focused on these at-risk groups may prove most useful in reducing LOS for pediatric asthma hospitalizations.
哮喘是儿科住院治疗的主要原因,但对于哮喘住院治疗的住院时间(LOS)相关因素知之甚少。本研究的目的是确定与儿科哮喘住院治疗LOS相关的因素。
使用儿科健康信息系统(PHIS)对2011年从42家PHIS医院出院的2至17岁原发性哮喘诊断患者进行队列研究。检查了社会人口统计学、时间和健康状况因素。在调整疾病严重程度(SOI)后,进行二元和广义估计方程逻辑回归分析以确定与LOS相关的因素。
共有25,900名儿童住院,平均LOS为1.9天。在二元分析中,患有复杂慢性病(CCC)的患者平均LOS更长(p < 0.01)(3.1天,非CCC患者为1.8天),青少年也是如此(2至5岁患者为2.3天,2至5岁患者为1.8天)。在多变量分析中,阻塞性睡眠呼吸暂停(OSA;OR 2.3;95% CI:1.8 - 2.9)、年龄较大(OR 1.3;95% CI:1.2 - 1.4)、肥胖(OR 1.3;95% CI:1.1 - 1.4)、CCC(OR 1.3;95% CI:1.1 - 1.4)、冬季入院(OR 1.2;95% CI:1.1 - 1.4)、女性(OR 1.1;95% CI:1.1 - 1.3)和周末入院(OR 1.1;95% CI:1.03 - 1.2)哮喘LOS > 2天的几率更高。
在调整SOI后,OSA、年龄较大、肥胖、CCC、冬季和周末入院以及女性与儿科哮喘住院治疗的LOS延长有关。研究结果表明,针对这些高危人群的干预措施可能对减少儿科哮喘住院治疗的LOS最有用。