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哮喘儿童阻塞性睡眠呼吸暂停:一项关于患病率和危险因素的横断面研究。

Obstructive sleep apnea in asthmatic children: a cross-sectional study about prevalence and risk factors.

机构信息

Universidade Federal de São Paulo, Departamento de Psicobiologia, São Paulo, SP, Brazil.

Universidade Federal de São Paulo, Departamento de Psicobiologia, São Paulo, SP, Brazil; Universidade Federal de São Paulo, Departamento de Medicina Interna, São Paulo, SP, Brazil.

出版信息

J Pediatr (Rio J). 2023 Sep-Oct;99(5):443-448. doi: 10.1016/j.jped.2023.03.005. Epub 2023 May 3.

Abstract

OBJECTIVES

Primary objectives were to analyze the prevalence of obstructive sleep apnea in (1) boys and girls, and (2) severe asthma versus moderate and mild cases. The authors hypothesized that girls and severe asthma would have a higher prevalence of obstructive sleep apnea.

METHODS

Cross-sectional evaluation of asthmatic children attending a tertiary Pediatric Pulmonology clinic. The authors performed a history, physical examination, pulmonary function test, and home sleep apnea test.

RESULTS

The authors studied 80 consecutive patients, 7-18 years old, mean age of 11.6 years (standard deviation 2.7), 51.3% female, and 18.5% obese. Pulmonary function tests were obtained from 80 volunteers, 45% with obstruction pattern. Home sleep apnea tests were available from 76 volunteers, with a mean obstructive respiratory index of 1.8 events/h. Obstructive sleep apnea was found in 49 volunteers (61.2%). The authors did not find associations between obstructive sleep apnea and sex or asthma severity.

CONCLUSIONS

Obstructive sleep apnea was frequent among these asthmatic children. Sex and asthma severity were not risk factors. Considering the interrelationship of both diseases, it is worth keeping in mind the possibility of obstructive sleep apnea among children and teenagers with asthma.

摘要

目的

主要目的是分析(1)男孩和女孩以及(2)重度哮喘与中、轻度哮喘病例中阻塞性睡眠呼吸暂停的患病率。作者假设女孩和重度哮喘的阻塞性睡眠呼吸暂停患病率更高。

方法

对在三级儿科肺病诊所就诊的哮喘儿童进行横断面评估。作者进行了病史、体格检查、肺功能检查和家庭睡眠呼吸暂停测试。

结果

作者研究了 80 名连续的患者,年龄 7-18 岁,平均年龄为 11.6 岁(标准差 2.7),51.3%为女性,18.5%为肥胖。80 名志愿者进行了肺功能检查,其中 45%存在阻塞模式。76 名志愿者进行了家庭睡眠呼吸暂停测试,平均阻塞性呼吸指数为 1.8 次/小时。49 名志愿者(61.2%)存在阻塞性睡眠呼吸暂停。作者未发现阻塞性睡眠呼吸暂停与性别或哮喘严重程度之间存在关联。

结论

这些哮喘儿童中阻塞性睡眠呼吸暂停很常见。性别和哮喘严重程度不是危险因素。考虑到这两种疾病的相互关系,值得注意的是,哮喘儿童和青少年中可能存在阻塞性睡眠呼吸暂停。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b07a/10492151/e221b756704d/gr1.jpg

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