Division of Asthma Research, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Ave, Cincinnati, OH, 45229, USA.
Division of Epidemiology, Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
J Transl Med. 2024 Jan 4;22(1):22. doi: 10.1186/s12967-023-04826-9.
This study addresses the limited research on racial disparities in asthma hospitalization outcomes, specifically length of stay (LOS) and readmission, across the U.S.
We analyzed in-patient and emergency department visits from the All of Us Research Program, identifying various risk factors (demographic, comorbid, temporal, and place-based) associated with asthma LOS and 30-day readmission using Bayesian mixed-effects models.
Of 17,233 patients (48.0% White, 30.7% Black, 19.7% Hispanic/Latino, 1.3% Asian, and 0.3% Middle Eastern and North African) with 82,188 asthma visits, Black participants had 20% shorter LOS and 12% higher odds of readmission, compared to White participants in multivariate analyses. Public-insured patients had 14% longer LOS and 39% higher readmission odds than commercially insured patients. Weekend admissions resulted in a 12% shorter LOS but 10% higher readmission odds. Asthmatics with chronic diseases had a longer LOS (range: 6-39%) and higher readmission odds (range: 9-32%) except for those with allergic rhinitis, who had a 23% shorter LOS.
A comprehensive understanding of the factors influencing asthma hospitalization, in conjunction with diverse datasets and clinical-community partnerships, can help physicians and policymakers to systematically address racial disparities, healthcare utilization and equitable outcomes in asthma care.
本研究针对美国哮喘住院结局(尤其是住院时间[LOS]和再入院率)方面种族差异的研究有限的问题,进行了研究。
我们分析了“所有人研究计划”中的住院和急诊就诊数据,使用贝叶斯混合效应模型确定了与哮喘 LOS 和 30 天再入院相关的各种风险因素(人口统计学、合并症、时间和地点相关)。
在 17233 名患者(48.0%为白人,30.7%为黑人,19.7%为西班牙裔/拉丁裔,1.3%为亚洲人,0.3%为中东和北非)的 82188 次哮喘就诊中,与白人患者相比,黑人患者的 LOS 缩短了 20%,再入院率增加了 12%。在多变量分析中,公共保险患者的 LOS 延长了 14%,再入院率增加了 39%,而商业保险患者的 LOS 延长了 14%,再入院率增加了 39%。周末入院导致 LOS 缩短 12%,但再入院率增加 10%。除了患有过敏性鼻炎的患者外,患有慢性疾病的哮喘患者的 LOS 延长(范围:6%-39%)和再入院率增加(范围:9%-32%),患有过敏性鼻炎的患者的 LOS 缩短 23%。
全面了解影响哮喘住院的因素,结合多样化的数据集和临床社区合作伙伴关系,可帮助医生和决策者系统地解决种族差异、医疗保健利用和哮喘护理方面的公平结局问题。