Department of Chemical Engineering The University of Michigan 3414 GGBL, 2300 Hayward Ann Arbor, MI 4809.
Macromolecular Science and Engineering The University of Michigan Ann Arbor, MI 4809.
Adv Mater. 2009 Dec 28;21(48):4920-4925. doi: 10.1002/adma.200901971. Epub 2009 Sep 18.
Biocompatible anisotropic polymer particles with bipolar affinity towards human endothelial cells are a novel type of building blocks for microstructured bio-hybrid materials. Functional polarity due to two biologically distinct hemispheres has been achieved by synthesis of anisotropic particles via electro-hydrodynamic co-jetting of two different polymer solutions and subsequent selective surface modification.
具有双亲和性的生物相容性各向异性聚合物颗粒对人内皮细胞具有亲和性,是一种新型的微结构生物杂化材料构建基块。通过两种不同聚合物溶液的电动力学共喷射和随后的选择性表面改性,合成各向异性颗粒,从而赋予功能性各向异性,实现两个具有生物学差异的半球。