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[主动脉炎:三例报告]

[Aortitis: report of three cases].

作者信息

Wurmann Pamela, Sabugo Francisca, Cruz Julio, Díaz Gonzalo, Sánchez Felipe, Pino Sandra, Pezo Ninette, Díaz Juan Carlos, Fernández Cristina

出版信息

Rev Med Chil. 2014 Jul;142(7):924-9. doi: 10.4067/S0034-98872014000700015.

Abstract

Aortitis is a nonspecific term that describes an inflammation of the aortic wall caused by inflammatory, infectious, paraneoplastic and idiopathic diseases. The symptoms are variable and nonspecific; therefore a high level of clinical suspicion is required to diagnose it. It is often an incidental finding while looking for other diagnoses and it is confirmed mainly through imaging studies. We report three cases of aortitis: A 29-year-old woman presenting with alopecia, oral and nasal ulcers and positive antinuclear antibodies. A CAT scan showed a segmental thickening of thoracic aorta, with dilated and stenotic areas. She was successfully treated with steroids, hydroxychloroquine, cyclophosphamide and azathioprine. A 41-year-old male presenting with dorsal pain and cough. The CAT scan showed an extra-intimal thickening of the descending aorta and stenosis of the celiac artery. The final diagnosis was a polyangiitis and was treated with steroids, cyclophosphamide and azathioprine. A 28-year-old woman presenting with pain in the left upper abdomen. Imaging studies showed a thickening of the aortic arch and subclavian artery. The final diagnosis was sarcoidosis and the patient was treated with prednisone.

摘要

主动脉炎是一个非特异性术语,用于描述由炎症性、感染性、副肿瘤性和特发性疾病引起的主动脉壁炎症。其症状多样且不具特异性;因此,诊断该病需要高度的临床怀疑。它常在寻找其他诊断时偶然发现,主要通过影像学检查确诊。我们报告三例主动脉炎病例:一名29岁女性,出现脱发、口腔和鼻溃疡以及抗核抗体阳性。计算机断层扫描显示胸主动脉节段性增厚,伴有扩张和狭窄区域。她接受了类固醇、羟氯喹、环磷酰胺和硫唑嘌呤治疗,效果良好。一名41岁男性,出现背痛和咳嗽。计算机断层扫描显示降主动脉内膜外增厚以及腹腔动脉狭窄。最终诊断为多血管炎,接受了类固醇、环磷酰胺和硫唑嘌呤治疗。一名28岁女性,出现左上腹疼痛。影像学检查显示主动脉弓和锁骨下动脉增厚。最终诊断为结节病,患者接受了泼尼松治疗。

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