Jolliffe Rachel, Seers Helen, Jackson Sarah, Caro Elena, Weeks Laura, Polley Marie J
Penny Brohn Cancer Care, Pill, Bristol, UK.
University of Granada, Granada, Spain.
Integr Cancer Ther. 2015 Jan;14(1):26-34. doi: 10.1177/1534735414555809. Epub 2014 Nov 10.
Measure Yourself Concerns and Wellbeing (MYCaW) is a patient-centered questionnaire that allows cancer patients to identify and quantify the severity of their "concerns" and "wellbeing," as opposed to using a predetermined list. MYCaW administration is brief and aids in prioritizing treatment approaches. Our goal was to assess the convergent validity and responsiveness of MYCaW scores over time, the generalizability of the existing qualitative coding framework in different complementary and integrative oncology settings and content validity.
Baseline and 6-week follow-up data (n = 82) from MYCaW and FACIT-SpEx questionnaires were collected for a service evaluation of the Living Well with the Impact of Cancer course at Penny Brohn Cance Care. MYCaW convergent validity was determined using Spearman's rank correlation test, and responsiveness indices assessed score changes over time. The existing qualitative coding framework was reviewed using a new data set (n = 158) and coverage of concern categories compared with items of existing outcome measures.
Good correlation between MYCaW and FACIT-SpEx score changes were achieved (r = -0.57, P ≥ .01). MYCaW Profile and Concern scores were highly responsive to change: standardized response mean = 1.02 and 1.08; effect size = 1.26 and 1.22. MYCaW change scores showed the anticipated gradient of change according to clinically relevant degrees of change. Categories, including "spirituality," "weight change," and "practical concerns" were added to the coding framework to improve generalizability.
MYCaW scores were highly responsive to change, allowing personalized patient outcomes to be quantified; the qualitative coding framework appears generalizable across different integrative oncology settings and has broader coverage of patient-identified concerns compared with existing cancer-related patient-reported outcome measures.
“自我关注与幸福感测评”（MYCaW）是一份以患者为中心的问卷，它使癌症患者能够识别并量化其“关注”和“幸福感”的严重程度，而非使用预先确定的列表。MYCaW的管理过程简短，有助于确定治疗方法的优先级。我们的目标是评估MYCaW评分随时间的收敛效度和反应性、现有定性编码框架在不同补充与整合肿瘤学环境中的可推广性以及内容效度。
收集了来自MYCaW和FACIT-SpEx问卷的基线及6周随访数据（n = 82），用于对彭妮·布罗恩癌症关怀中心的“与癌症影响共生活得好”课程进行服务评估。使用斯皮尔曼等级相关检验确定MYCaW的收敛效度，并通过反应性指标评估随时间的评分变化。使用一个新数据集（n = 158）对现有的定性编码框架进行审查，并将关注类别覆盖范围与现有结局指标的项目进行比较。
MYCaW与FACIT-SpEx评分变化之间实现了良好的相关性（r = -0.57，P≥.01）。MYCaW概况和关注评分对变化高度敏感：标准化反应均值分别为1.02和1.08；效应量分别为1.26和1.22。MYCaW变化评分显示出根据临床相关变化程度预期的变化梯度。编码框架中增加了包括“灵性”“体重变化”和“实际问题”等类别，以提高可推广性。
MYCaW评分对变化高度敏感，能够量化个性化的患者结局；定性编码框架似乎在不同的整合肿瘤学环境中具有可推广性，与现有的癌症相关患者报告结局指标相比，对患者确定的关注问题覆盖范围更广。
