对羟乙基淀粉溶液使用的担忧。
Concerns over use of hydroxyethyl starch solutions.
作者信息
Hartog Christiane S, Natanson Charles, Sun Junfeng, Klein Harvey G, Reinhart Konrad
机构信息
Department of Anaesthesiology and Intensive Care Medicine, Centre for Sepsis Care and Control, Jena University Hospital, D-07747 Jena, Germany.
Critical Care Medicine Department, National Institutes of Health, Bethesda, MD 20892, USA.
出版信息
BMJ. 2014 Nov 10;349:g5981. doi: 10.1136/bmj.g5981.
Abstract
Large trials have shown that hydroxyethyl starch increases the risk of death, kidney injury, and bleeding. However, an EMA review last year permitted continued use in some patients, overturning an earlier decision to withdraw the product completely. discuss the evidence and call on doctors to avoid using starch formulations
摘要
大型试验表明，羟乙基淀粉会增加死亡、肾损伤和出血风险。然而，欧洲药品管理局（EMA）去年的一项审查允许在某些患者中继续使用，推翻了此前完全撤市该产品的决定。讨论了相关证据，并呼吁医生避免使用淀粉制剂
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