Hartog Christiane S, Natanson Charles, Sun Junfeng, Klein Harvey G, Reinhart Konrad
Department of Anaesthesiology and Intensive Care Medicine, Centre for Sepsis Care and Control, Jena University Hospital, D-07747 Jena, Germany.
Critical Care Medicine Department, National Institutes of Health, Bethesda, MD 20892, USA.
BMJ. 2014 Nov 10;349:g5981. doi: 10.1136/bmj.g5981.
Large trials have shown that hydroxyethyl starch increases the risk of death, kidney injury, and bleeding. However, an EMA review last year permitted continued use in some patients, overturning an earlier decision to withdraw the product completely. discuss the evidence and call on doctors to avoid using starch formulations
大型试验表明，羟乙基淀粉会增加死亡、肾损伤和出血风险。然而，欧洲药品管理局（EMA）去年的一项审查允许在某些患者中继续使用，推翻了此前完全撤市该产品的决定。讨论了相关证据，并呼吁医生避免使用淀粉制剂
