Butterworth K T, Prise K M, Verhaegen F
1 Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, Ireland.
Br J Radiol. 2015 Jan;88(1045):20140634. doi: 10.1259/bjr.20140634.
Radiation biology is being transformed by the implementation of small animal image-guided precision radiotherapy into pre-clinical research programmes worldwide. We report on the current status and developments of the small animal radiotherapy field, suggest criteria for the design and execution of effective studies and contend that this powerful emerging technology, used in combination with relevant small animal models, holds much promise for translational impact in radiation oncology.
小动物图像引导精确放疗在全球临床前研究项目中的应用正在改变放射生物学。我们报告了小动物放疗领域的现状和发展,提出了有效研究设计和实施的标准,并认为这种强大的新兴技术与相关小动物模型结合使用,在放射肿瘤学的转化影响方面具有很大潜力。