Sannareddy Rajesh Reddy, Rambabu K, Kumar Vinay Ec, Gnana Ratnam Boola, Ranjan Alok
Department of Neurosurgery, Apollo Health City, Hyderabad, Andhra Pradesh, India.
Neurol India. 2014 Sep-Oct;62(5):532-9. doi: 10.4103/0028-3886.144453.
Transnasal endoscopic repair has become the treatment of choice for most anterior cranial and all sphenoid sinus breaches. The aim of this paper is to evaluate the results of endoscopic management of cerebrospinal fluid (CSF) rhinorrhea in a tertiary care center in South India.
A retrospective analysis of 40 consecutive patients who underwent endoscopic repair of CSF rhinorrhea between 2010 and 2013 was performed. Endoscopic procedure consisted of defining the defect and removal of mucosa for 3-4 mm surrounding it. Repair was done using septal cartilage (for defects involving sphenoid sinus where sinus was packed with fat), fascia lata, oxidized cellulose, and fibrin sealant. Lumbar drain was placed for 2-4 days in selected cases. A lumbar-peritoneal shunt was inserted in patients with spontaneous CSF rhinorrhea and high opening lumbar CSF pressure.
Spontaneous CSF leaks were more common in middle-aged females, whereas posttraumatic CSF leaks were common in young adult males. The success rates following first surgery for patients with posttraumatic, spontaneous, and postprocedural CSF leaks were 85.7, 81.8, and 75%, respectively, which improved to 95.7, 100, and 100% following second procedure, respectively. Technical failures, poor graft uptake because of radiation therapy, location of leak in the lateral sphenoid recess, lumbar peritoneal shunt malfunction, and poor healing of skull base fractures were responsible for recurrence of leak.
Team work between neurosurgeons and otorhinolaryngologists with attention to identification of site of leak, preparation of graft bed, securing the graft in place, and postoperative care is critical to achieve a high level of success for endoscopic repair of CSF rhinorrhea.
经鼻内镜修复术已成为大多数前颅底和所有蝶窦破裂的首选治疗方法。本文旨在评估印度南部一家三级医疗中心内镜治疗脑脊液鼻漏的效果。
对2010年至2013年间连续40例行脑脊液鼻漏内镜修复术的患者进行回顾性分析。内镜手术包括确定缺损并切除其周围3 - 4毫米的黏膜。使用鼻中隔软骨(用于涉及蝶窦且蝶窦用脂肪填充的缺损)、阔筋膜、氧化纤维素和纤维蛋白密封剂进行修复。部分病例放置腰大池引流2 - 4天。对自发性脑脊液鼻漏且腰穿脑脊液压力高的患者插入腰大池 - 腹腔分流管。
自发性脑脊液漏在中年女性中更为常见,而创伤后脑脊液漏在年轻成年男性中较为常见。创伤后、自发性和术后脑脊液漏患者首次手术后的成功率分别为85.7%、81.8%和75%,第二次手术后分别提高到95.7%、100%和100%。技术失败、放疗导致的移植物吸收不良、蝶窦外侧隐窝漏口位置、腰大池 - 腹腔分流管故障以及颅底骨折愈合不良是漏口复发的原因。
神经外科医生和耳鼻咽喉科医生之间的团队合作,注重漏口部位的识别、移植物床的准备、移植物的固定以及术后护理,对于脑脊液鼻漏内镜修复术取得高成功率至关重要。