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[电离辐射对单价阳离子调节肾脏钠钾ATP酶活性的影响]

[The effect of ionizing radiation on the regulation of the Na,K-ATPase activity of the kidney by univalent cations].

作者信息

Shainskaia A M, Annenkova S V, Egorova E G, Dboretskiĭ A I

出版信息

Radiobiologiia. 1989 Jan-Feb;29(1):121-3.

PMID:2538859
Abstract

The effect of ionizing radiation of 0.206 C/kg on the kinetics of activation of rat kidney Na,K-ATPase preparation by Na and K ions was studied as an index of possible qualitative and quantitative changes in the properties of the enzyme. Ionizing radiation was shown not only to increase the enzyme activity but also to change the optimal rate of ATP hydrolysis by Na,K-ATPase and to induce some differences in the shape of the curve for Na,K-ATPase dependence upon Na-sodium//potassium ion ratio in the incubation medium.

摘要

研究了0.206 C/kg的电离辐射对大鼠肾脏Na,K - ATP酶制剂被Na和K离子激活的动力学的影响,以此作为该酶性质可能发生的定性和定量变化的指标。结果表明,电离辐射不仅会增加酶活性,还会改变Na,K - ATP酶水解ATP的最佳速率,并在孵育介质中诱导出Na,K - ATP酶对钠/钾离子比率依赖性曲线形状的一些差异。

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