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[使用简化数学模型描述单价阳离子对钠钾ATP酶的激活作用]

[Description of Na, K-ATPase activation by monovalent cations using a simplified mathematical model].

作者信息

Ernandes Kh L

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1985(5):108-10.

PMID:2992616
Abstract

A simple mathematic model describing the activation Na,K-ATPase system by univalent cations is proposed. The constants for the enzyme activation values by each of the ions in the presence of a fixed concentration of the other ion have been calculated. The substitution of these values into the common equation describing the behaviour of the whole system according to the given model gives the curve of Na,K-ATPase activity change in dependence of Na/K ration at the same total concentration 150 mM. The experimental points correspond to the curve.

摘要

提出了一个描述单价阳离子激活钠钾-ATP酶系统的简单数学模型。计算了在另一种离子固定浓度存在时，每种离子对酶激活值的常数。将这些值代入根据给定模型描述整个系统行为的通用方程，得到了在总浓度为150 mM时，钠钾-ATP酶活性随钠/钾比率变化的曲线。实验点与该曲线相符。

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