Heintz P, Ehrenheim C
Abteilung Nuklearmedizin und spezielle Biophysik, Medizinische Hochschule Hannover.
Rofo. 1989 Mar;150(3):297-306. doi: 10.1055/s-2008-1047027.
47 patients with liver tumours (haemangioma, focal nodular hyperplasia, hepatocellular carcinoma) underwent MRI of the liver before and after i.v. injection of 0.2 ml./kg. gadolinium-DTPA in addition to other imaging methods. The demarcation of focal nodular hyperplasia is not influenced by use of the contrast agent as it almost behaves like surrounding normal liver tissue, thus only indirectly facilitating its identification. With regard to liver haemangiomas that show the most intensive uptake of gadolinium-DTPA, the contrast enhanced image does not reach the contrast and sensitivity of a native T2-weighted SE image, especially in cases of small haemangiomas. The contrast agent is helpful, however, in the recognition of large cavernous haemangiomas that are partially fibrotic or thrombotic. Emphasis is given to the contrast agent in hepatomas: gadolinium-DTPA presents a pattern of uptake and distribution frequently found in hepatocellular carcinoma providing additional information on the delineation of internal tumour details.
47例肝脏肿瘤(血管瘤、局灶性结节性增生、肝细胞癌)患者除接受其他成像方法外,还在静脉注射0.2 ml/kg钆喷酸葡胺前后接受了肝脏MRI检查。局灶性结节性增生的边界不受造影剂使用的影响,因为它的表现几乎与周围正常肝组织相同,因此只能间接促进其识别。对于钆喷酸葡胺摄取最强烈的肝脏血管瘤,增强造影图像达不到原始T2加权SE图像的对比度和敏感性,尤其是在小血管瘤的情况下。然而,造影剂有助于识别部分纤维化或血栓形成的大型海绵状血管瘤。重点介绍了造影剂在肝癌中的应用:钆喷酸葡胺呈现出肝细胞癌中常见的摄取和分布模式,为描绘肿瘤内部细节提供了额外信息。