玻璃体内注射贝伐单抗后的伤口渗漏。
Wound leak after intravitreal injection of bevacizumab.
作者信息
Wickremasinghe Sanjeewa S, Michalova Kira, Guymer Robyn H, Harper C Alex
机构信息
From the *Medical Retina Unit, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia; and the †Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia.
出版信息
Retin Cases Brief Rep. 2008 Summer;2(3):245-6. doi: 10.1097/ICB.0b013e3181652477.
PURPOSE
To report an occurrence of wound leak from the injection site after intravitreal injection of bevacizumab. A possible underlying etiology is discussed.
METHODS
A single injection of bevacizumab was given for treatment of choroidal neovascularization complicating previous choroidal rupture.
RESULTS
A reduction in vision and hypotony were noted 1 day after injection. With conservative management, there was spontaneous resolution of the wound leak.
CONCLUSION
The risk of wound leak after intravitreal injection may be higher for younger patients and those who have undergone vitrectomy. All patients and clinicians, however, should be alert to vision decline after injection, and prompt evaluation should be performed to ascertain the cause. For patients with persistent wound leak, surgical intervention may be required.
目的
报告玻璃体腔内注射贝伐单抗后注射部位发生伤口渗漏的情况，并讨论可能的潜在病因。
方法
单次注射贝伐单抗用于治疗先前脉络膜破裂并发的脉络膜新生血管。
结果
注射后1天出现视力下降和低眼压。经保守治疗，伤口渗漏自行消退。
结论
玻璃体腔内注射后伤口渗漏的风险在年轻患者和接受过玻璃体切除术的患者中可能更高。然而，所有患者和临床医生都应警惕注射后视力下降，并应及时进行评估以确定原因。对于伤口渗漏持续的患者，可能需要手术干预。
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