Lone Farah, Sultan Abdul H, Stankiewicz Aleksandra, Thakar Ranee, Wieczorek Andrzej Pawel
Subspecialty trainee Urogynaecology, Department of Obstetrics and Gynaecology, Croydon University Hospital, Croydon, UK.
Department of Obstetrics and Gynaecology, Croydon University Hospital, Croydon, UK.
Springerplus. 2014 Oct 20;3:619. doi: 10.1186/2193-1801-3-619. eCollection 2014.
To assess the urethral vascularity in continent women using colour doppler high frequency endovaginal ultrasonography (EVUS).
We recruited 61 continent women attending gynaecology clinics between July and October 2009. Exclusion criteria included symptoms of urinary incontinence, voiding dysfunction, pelvic organ prolapse or urinary tract infection. The participants underwent EVUS using high frequency (9-12 MHz) biplane transducer (type 8848 BK Medical), according to a standardised protocol. Colour Doppler US was performed in sagittal plane and in transverse plane at the level of the mid-urethra. Ten seconds video files were recorded and following vascular parameters: flow velocity (Vmix), area of the vessels (Amix), intensity of vascularity (Imix), pulsatility index (PImix) and resistance index (RImix) was evaluated.
There were 30 nulliparous (49.2%) women and 31 multiparous women (50.8%) with a mean (±SD) age of 32 (±4) and 46 (±6) years respectively. Significant impairment of vascularity was observed in multiparous patients as compared to nulliparous and was reflected by increased values of RImix (p < 0.001) and PImix (p < 0.001), and decreased values of Vmix (p < 0.001), Amix (p < 0.001), Imix (p < 0.001) in axial and midsagittal sections of the midurethra. A significant decrease of mean value ± SD of Imix- from 0.02 ± 0.02 in nulliparous to 0.005 ± 0.01 in multiparous was observed. Cronbach alpha, used to assess vascular correlations and parity demonstrated a reduction when expressed only for vascular parameters, indicating that number of deliveries is an important factor while assessing urethral vascularity.
Compared to continent nulliparous women, continent multiparous women demonstrated a significant reduction in the vascularity parameters in all measured variables when parity was accounted for.
This study provides the basis for further research in assessing urethral vascularity in women.
使用彩色多普勒高频经阴道超声检查（EVUS）评估控尿女性的尿道血管情况。
我们招募了2009年7月至10月期间到妇科门诊就诊的61名控尿女性。排除标准包括尿失禁症状、排尿功能障碍、盆腔器官脱垂或尿路感染。参与者按照标准化方案，使用高频（9 - 12MHz）双平面探头（8848 BK Medical型）进行EVUS检查。在尿道中段水平的矢状面和横断面上进行彩色多普勒超声检查。记录10秒的视频文件，并评估以下血管参数：流速（Vmix）、血管面积（Amix）、血管强度（Imix）、搏动指数（PImix）和阻力指数（RImix）。
有30名未生育女性（49.2%）和31名经产妇（50.8%），平均（±标准差）年龄分别为32（±4）岁和46（±6）岁。与未生育女性相比，经产妇的血管情况有显著损害，表现为尿道中段轴向和矢状中切面上RImix（p < 0.001）和PImix（p < 0.001）值升高，Vmix（p < 0.001）、Amix（p < 0.001）、Imix（p < 0.001）值降低。观察到Imix的平均值±标准差从未生育女性的0.02±0.02显著降至经产妇的0.005±0.01。用于评估血管相关性和生育情况的Cronbach α系数仅针对血管参数表示时有所降低，表明分娩次数是评估尿道血管情况时的一个重要因素。
与控尿的未生育女性相比，在考虑生育情况时，控尿的经产妇在所有测量变量中的血管参数均显著降低。
本研究为进一步评估女性尿道血管情况的研究提供了基础。
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