Zhu Wei, Jiang Chunming, Zheng Xi, Zhang Miao, Guo Hongqian, Yan Xiang
Department of Nephrology, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, People's Republic of China.
Int Urol Nephrol. 2015 Feb;47(2):377-82. doi: 10.1007/s11255-014-0877-9. Epub 2014 Nov 14.
Currently, most ESRD patients are treated with open surgical technique or with laparoscopic technique. In this study, we examined the role of the ureteroscope-assisted "Mini-Perc" technique versus the modified open surgery in the treatment of ESRD in a prospective randomized manner.
A total of 72 patients with chronic renal failure were prospectively randomized for the ureteroscope-assisted "Mini-Perc" technique or modified open surgery. Intraoperative and postoperative morbidity, incision size, dose of local anesthesia, operative time, hospital stay, and initial catheter survival and follow-up were compared for both methods.
"Mini-Perc" group was associated with shorter incision size, operative time, and hospital stay, with lower dose of local anesthesia and incidence of bloody ascites. Two of five patients with the history of abdominal surgery in "Mini-Perc" group required adhesiolysis under direct vision of telescope. All adhesions were easily dissected. All complications of leakage (8.1 %) and incisional hernia (2.7 %) occurred in the open surgery group, but a difference of no significant value with "Mini-Perc" group (p = 0.2400, p = 1.0000). There was no any other significant difference in common complications between two groups. After 2 years of follow-up, 54 patients (75 %) survived with their initial PD catheter. The overall death was 5 (6.9 %).
Compared to modified open surgical technique, the ureteroscope-assisted "Mini-Perc" technique can be used to achieve the same clinical efficacy for placement of peritoneal dialysis catheters in ESRD patients, and it carries minimal morbidity.
目前,大多数终末期肾病(ESRD)患者采用开放手术技术或腹腔镜技术进行治疗。在本研究中,我们以前瞻性随机方式研究了输尿管镜辅助“Mini-Perc”技术与改良开放手术在ESRD治疗中的作用。
总共72例慢性肾衰竭患者被前瞻性随机分为接受输尿管镜辅助“Mini-Perc”技术或改良开放手术。比较了两种方法的术中及术后发病率、切口大小、局部麻醉剂量、手术时间、住院时间、初始导管存活情况及随访情况。
“Mini-Perc”组的切口尺寸、手术时间和住院时间较短,局部麻醉剂量较低,血性腹水发生率较低。“Mini-Perc”组中有腹部手术史的5例患者中有2例需要在输尿管镜直视下进行粘连松解。所有粘连均易于分离。开放手术组发生了所有渗漏并发症(8.1%)和切口疝并发症(2.7%),但与“Mini-Perc”组相比差异无统计学意义(p = 0.2400,p = 1.0000)。两组常见并发症之间无任何其他显著差异。经过2年随访,54例患者(75%)的初始腹膜透析导管存活。总死亡率为5例(6.9%)。
与改良开放手术技术相比,输尿管镜辅助“Mini-Perc”技术在ESRD患者腹膜透析导管置入中可达到相同的临床疗效,且发病率极低。