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经腹膜透析导管的“半 Perc”与开放式手术置管方法的分析:一项非劣效性队列研究。

An analysis of the "Half-Perc" versus open surgical placement method for a peritoneal dialysis catheter: a non-inferiority cohort study.

机构信息

The Second Clinical College of Guangzhou University of Chinese Medicine, No.111 Dade Road, Guangzhou, 510405, China.

Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, No.111 Dade Road, Guangzhou, 510120, China.

出版信息

BMC Nephrol. 2020 Jul 20;21(1):288. doi: 10.1186/s12882-020-01936-0.

Abstract

BACKGROUND

Most end-stage renal disease (ESRD) patients undergo open surgical techniques for peritoneal dialysis (PD) catheter placement. An alternative method to PD catheter implantation is the half-percutaneous ("Half-Perc") technique based on a modified trocar that is performed by a nephrologist. The single-center, retrospective, observational, cohort study presented here aimed to compare the effects of the "Half-Perc" technique with the traditional open surgery on peritoneal catheter insertion.

METHODS

From January 2015 to January 2018, 240 ESRD patients who received initial PD catheter placement were divided into two groups based on the "Half-Perc" technique or open surgery. All patients were followed up for 365 days or until loss of initial PD catheter or death. Prism 5 software was used to analyze baseline characteristics, operation-related parameters, mechanical complications and clinical outcomes.

RESULTS

The "Half-Perc" technique showed shorter operation time, shorter incision length, lower postoperative pain scores and quick initiation of the PD program compared to the open surgery. After the 365-day follow-up, the "Half-Perc" group showed a higher rate of catheter dysfunction (4% versus 0.9%) that was corrected by conservative treatment in most patients and a lower rate of peritonitis (4% versus 9.6%) but mechanical complications and clinical outcomes did not differ between the two groups. There was also no significant difference based on overall patient mortality or catheter removal. One-year initial catheter survival and true catheter survival were not statistically different between the groups.

CONCLUSION

The "Half-Perc" placement of the PD catheter using a modified metal trocar appears to be a non-inferior alternative method and carries minimal invasiveness and risk compared to open surgical placement.

摘要

背景

大多数终末期肾病(ESRD)患者接受开放式手术进行腹膜透析(PD)导管放置。PD 导管植入的替代方法是基于改良套管针的半经皮(“Half-Perc”)技术,由肾病学家进行操作。本单中心回顾性观察队列研究旨在比较“Half-Perc”技术与传统开放式手术对腹膜导管插入的影响。

方法

从 2015 年 1 月至 2018 年 1 月,根据“Half-Perc”技术或开放式手术将 240 例接受初始 PD 导管放置的 ESRD 患者分为两组。所有患者均随访 365 天或直至初始 PD 导管丢失或死亡。使用 Prism 5 软件分析基线特征、手术相关参数、机械并发症和临床结局。

结果

与开放式手术相比,“Half-Perc”技术具有操作时间更短、切口长度更短、术后疼痛评分更低和 PD 方案启动更快的特点。在 365 天随访后,“Half-Perc”组的导管功能障碍发生率(4%比 0.9%)更高,但大多数患者通过保守治疗得到纠正,腹膜炎发生率(4%比 9.6%)更低,但两组间机械并发症和临床结局无差异。两组患者的总体死亡率或导管去除率也无显著差异。两组患者的 1 年初始导管生存率和实际导管生存率无统计学差异。

结论

与开放式手术相比,使用改良金属套管针的“Half-Perc”PD 导管放置似乎是一种非劣效替代方法,具有微创性和低风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7828/7370485/caeca149cd04/12882_2020_1936_Fig1_HTML.jpg

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