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纤维肌痛和蛛网膜炎表现为一种急性脊柱疾病。

Fibromyalgia and arachnoiditis presented as an acute spinal disorder.

作者信息

Idris Zamzuri, Ghazali Faizul H, Abdullah Jafri M

机构信息

Center for Neuroscience Service and Research, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150 Kelantan, Malaysia ; Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150 Kelantan, Malaysia.

Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150 Kelantan, Malaysia.

出版信息

Surg Neurol Int. 2014 Oct 21;5:151. doi: 10.4103/2152-7806.143364. eCollection 2014.

Abstract

BACKGROUND

Adhesive arachnoiditis is a chronic, insidious condition that causes debilitating intractable pain and a range of other neurological problems. Its pathophysiology is not well understood. This manuscript discusses its presentations, which can mimic an acute spinal disorder, its hypothetical pathophysiology, treatment, and its relationship with fibromyalgia.

CASE DESCRIPTION

The authors present a case of a 47-year-old female who presented with clinical features mimicking an acute spinal disorder but later found to have an adhesive arachnoiditis. She was admitted following a trauma with complaints of back pain and paraplegia. On examination, there was marked tenderness over thoracolumbar spine with lower limbs upper motor neuron weakness. An urgent magnetic resonance imaging (MRI) of the spine revealed multiple lesions at her thoracic and lumbar spinal canals, which did not compress the spinal cord. Therefore, conservative management was initiated. Despite on regular therapies, her back and body pain worsened and little improvement in her limbs power was noted. Laminectomy was pursued and found to have spinal cord arachnoiditis. Subsequently, she was operated by other team members for multiple pelvic masses, which later proved to be benign. After gathering all the clinical information obtained at surgery and after taking detailed history inclusive of cognitive functions, diagnosis of an adhesive arachnoiditis syndrome was made. Currently, she is managed by neuropsychologist and pain specialist.

CONCLUSION

This case report highlights the importance of knowing an adhesive arachnoiditis syndrome - a rarely discussed pathology by the neurosurgeon, which discloses a significant relationship between immune and nervous systems.

摘要

背景

粘连性蛛网膜炎是一种慢性、隐匿性疾病,可导致使人衰弱的顽固性疼痛和一系列其他神经问题。其病理生理学尚未完全明确。本文讨论了其临床表现(可模仿急性脊柱疾病)、假定的病理生理学、治疗方法及其与纤维肌痛的关系。

病例描述

作者报告了一例47岁女性病例,该患者最初表现出模仿急性脊柱疾病的临床特征,但后来被诊断为粘连性蛛网膜炎。她因外伤后出现背痛和截瘫入院。检查发现胸腰椎有明显压痛,下肢存在上运动神经元无力。脊柱紧急磁共振成像(MRI)显示胸段和腰段椎管内有多个病变,但未压迫脊髓。因此,开始采取保守治疗。尽管进行了常规治疗,她的背部和全身疼痛仍加重,且肢体力量几乎没有改善。随后进行了椎板切除术,发现存在脊髓蛛网膜炎。随后,其他团队成员为她切除了多个盆腔肿块,后来证实这些肿块是良性的。在收集了手术中获得的所有临床信息并详细询问了包括认知功能在内的病史后,诊断为粘连性蛛网膜炎综合征。目前,她由神经心理学家和疼痛专家进行管理。

结论

本病例报告强调了了解粘连性蛛网膜炎综合征的重要性——这是神经外科医生很少讨论的一种病理情况,它揭示了免疫系统和神经系统之间的重要关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ece/4228496/3e23a7782859/SNI-5-151-g001.jpg

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