Asati Dinesh Prasad, Tiwari Anurag
Department of Dermatology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Consultant Dermatologist, Centre for Skin Diseases and Laser Treatment, Bhopal, Madhya Pradesh, India.
Indian Dermatol Online J. 2014 Oct;5(4):497-500. doi: 10.4103/2229-5178.142520.
Mastocytosis is a rare myeloid neoplasm characterized by abnormal proliferation and accumulation of mast cells in one or more organ systems including the skin, bone marrow, liver, spleen, lymph nodes and gastrointestinal tract. An infant presenting with bullous lesions is an even rarer clinical presentation of cutaneous mastocytosis. The symptoms and complications are mostly in proportion to the mast cell degranulation in tissues. Management is focused on preventing and treating this event. We report a three-month-old infant with bullous mastocytosis to enhance awareness about this rare diagnosis.
肥大细胞增多症是一种罕见的髓系肿瘤，其特征是肥大细胞在一个或多个器官系统（包括皮肤、骨髓、肝脏、脾脏、淋巴结和胃肠道）中异常增殖和积聚。一名出现水疱性病变的婴儿是皮肤肥大细胞增多症更为罕见的临床表现。症状和并发症大多与组织中的肥大细胞脱颗粒程度成正比。治疗重点是预防和治疗这一情况。我们报告一名患有水疱性肥大细胞增多症的三个月大婴儿，以提高对这种罕见诊断的认识。
