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Small Molecule PAI-1 Functional Inhibitor Attenuates Vascular Smooth Muscle Cell Migration and Survival: Implications for the Therapy of Vascular Disease.

作者信息

Simone Tessa M, Higgins Paul J

机构信息

Center for Cell Biology & Cancer Research, Albany Medical College, Albany, New York 12208.

出版信息

New Horiz Transl Med. 2014 Sep 1;2(1):16-19. doi: 10.1016/j.nhtm.2014.08.003.

Abstract
摘要

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本文引用的文献

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A plasminogen activator inhibitor-1 inhibitor reduces airway remodeling in a murine model of chronic asthma.
Am J Respir Cell Mol Biol. 2012 Jun;46(6):842-6. doi: 10.1165/rcmb.2011-0369OC. Epub 2012 Feb 9.
2
Ligation of macrophage Fcγ receptors recapitulates the gene expression pattern of vulnerable human carotid plaques.
PLoS One. 2011;6(7):e21803. doi: 10.1371/journal.pone.0021803. Epub 2011 Jul 21.
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The 'PAI-1 paradox' in vascular remodeling.
Thromb Haemost. 2008 Dec;100(6):984-91.
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Plasminogen activator inhibitor-1 protects endothelial cells from FasL-mediated apoptosis.
Cancer Cell. 2008 Oct 7;14(4):324-34. doi: 10.1016/j.ccr.2008.08.012.
8
Mechanism of inactivation of plasminogen activator inhibitor-1 by a small molecule inhibitor.
J Biol Chem. 2007 Mar 23;282(12):9288-96. doi: 10.1074/jbc.M611642200. Epub 2007 Feb 2.

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