a Faculty and Graduate School of Environment and Information Sciences , Yokohama National University , Yokohama , Kanagawa , Japan.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2014;31(12):1982-92. doi: 10.1080/19440049.2014.974686. Epub 2014 Nov 17.
The non-carcinogenic and carcinogenic risk of arsenic and lead to adults and children via daily dietary intake of food composites in Bangladesh was estimated. The target hazard quotients (THQs), hazard index (HI) and target carcinogenic risk (TR) were calculated to evaluate the non-carcinogenic and carcinogenic health risk from arsenic and lead. Most of the individual food composites contain a considerable amount of arsenic and lead. The highest mean concentrations of arsenic were found in cereals (0.254 mg kg⁻¹ fw) and vegetables (0.250 mg kg⁻¹ fw), and lead in vegetables (0.714 mg kg⁻¹ fw) and fish (0.326 mg kg⁻¹ fw). The results showed the highest THQs of arsenic in cereals and lead in vegetables for both adults and children which exceeded the safe limit (> 1) indicating that cereals and vegetables are the main food items contributing to the potential health risk. The estimated TR from ingesting dietary arsenic and lead from most of the foods exceeded 10⁻⁶, indicating carcinogenic risks for all adult people of the study area.
本研究估算了孟加拉国成年人和儿童通过日常饮食摄入食物混合物中砷和铅的非致癌和致癌风险。通过计算目标危害系数（THQ）、危害指数（HI）和目标致癌风险（TR），评估了砷和铅的非致癌和致癌健康风险。大多数个体食物混合物中都含有相当数量的砷和铅。谷物（0.254mgkg-1 fw）和蔬菜（0.250mgkg-1 fw）中砷的平均浓度最高，蔬菜（0.714mgkg-1 fw）和鱼类（0.326mgkg-1 fw）中铅的平均浓度最高。结果表明，砷的 THQ 最高的是谷物，铅的 THQ 最高的是蔬菜，这两项对于成年人和儿童均超过了安全限值（>1），表明谷物和蔬菜是导致潜在健康风险的主要食物。从大多数食物中摄入的饮食砷和铅的估计 TR 超过了 10-6，这表明研究区域所有成年人都存在致癌风险。
