Mezencio J M, de Souza W, Fonseca M E, Rebello M A
Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Brasil.
Arch Virol. 1989;104(3-4):299-308. doi: 10.1007/BF01315551.
The replication of Mayaro virus in Aedes albopictus cells, was studied by electron microscopy at various times post-infection. In infected cells we observed the presence of cytoplasmic vesicles containing viral nucleocapsids and mature virus particles but at no time did we detect virus budding into such vacuoles. Budding of virus through plasma membrane was rarely observed. Our results are discussed considering the possibility of the release of virus particles to the extracellular space by exocytosis.
通过电子显微镜在感染后的不同时间对马亚罗病毒在白纹伊蚊细胞中的复制进行了研究。在受感染的细胞中,我们观察到含有病毒核衣壳和成熟病毒颗粒的细胞质小泡的存在,但我们从未检测到病毒芽生到这样的液泡中。很少观察到病毒通过质膜芽生。我们结合通过胞吐作用将病毒颗粒释放到细胞外空间的可能性对结果进行了讨论。