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与肺手术后连续硬膜外阻滞相比,超声引导下连续胸椎旁阻滞提供了相当的镇痛效果,且低血压发作次数更少。

Ultrasound-guided continuous thoracic paravertebral block provides comparable analgesia and fewer episodes of hypotension than continuous epidural block after lung surgery.

作者信息

Okajima Hanae, Tanaka Osamu, Ushio Masahiro, Higuchi Yasuko, Nagai Yukiko, Iijima Katsuhiro, Horikawa Yoshio, Ijichi Kazuko

机构信息

Department of Anesthesiology, Nishi-Kobe Medical Center, 5-7-1 Kojidai, Nishiku, Kobe, Hyogo, 651-2273, Japan.

Department of Anesthesiology, Kakogawa West City Hospital, 384-1 Yonedachohiratsu, Kakogawa, Hyogo, 675-8611, Japan.

出版信息

J Anesth. 2015 Jun;29(3):373-378. doi: 10.1007/s00540-014-1947-y. Epub 2014 Nov 15.

DOI:10.1007/s00540-014-1947-y
PMID:25398399
Abstract

PURPOSE

Both paravertebral block (PVB) and thoracic epidural block (TEB) are recommended for postoperative pain relief after lung surgery. The addition of fentanyl to the anesthetic solution became popular for TEB because of the stronger effects; however, there have been few comparable trials about the addition of fentanyl to PVB. The purpose of this study was thus to compare postoperative analgesia, side effects, and complications between ultrasound-guided PVB (USG-PVB) and TEB with the addition of fentanyl to ropivacaine after lung surgery.

METHODS

We examined 90 consecutive patients (age 18-75 years) scheduled for video-assisted thoracic surgery (VATS). In both groups, all blocks (four blocks in USG-PVB and one block in TEB) and one catheter insertion were performed preoperatively. Continuous postoperative infusion (0.1% ropivacaine plus fentanyl at 0.4 mg/day) was undertaken for 36 h in both groups. The recorded data included the verbal rating scale (VRS) for pain, blood pressure, side effects, complications for 2 days, and overall satisfaction score.

RESULTS

There was no difference in the frequency of taking supplemental analgesics (twice or more frequently), or in VRS. Hypotension occurred significantly more frequently in TEB (n = 7/33) than in PVB (n = 1/36) (P = 0.02); on the other hand, the incidences of PONV and pruritus, as well as overall satisfaction score, were similar. There were no complications in both groups; however, the catheters migrated intrathoracically in four patients in PVB.

CONCLUSION

USG-PVB achieved similar pain relief and lowered the incidence of hypotension compared with TEB. We conclude that both blocks with the same concentration of ropivacaine and fentanyl can provide adequate postoperative analgesia for VATS.

摘要

目的

椎旁阻滞(PVB)和胸段硬膜外阻滞(TEB)均被推荐用于肺手术后的术后疼痛缓解。由于效果更强,在麻醉溶液中添加芬太尼在TEB中很流行;然而,关于在PVB中添加芬太尼的可比试验很少。因此,本研究的目的是比较肺手术后超声引导下PVB(USG-PVB)和添加芬太尼的TEB在术后镇痛、副作用和并发症方面的差异。

方法

我们检查了90例连续安排进行电视辅助胸腔镜手术(VATS)的患者(年龄18 - 75岁)。在两组中,所有阻滞(USG-PVB为四个阻滞点,TEB为一个阻滞点)和一次导管插入均在术前进行。两组均进行36小时的术后持续输注(0.1%罗哌卡因加0.4毫克/天芬太尼)。记录的数据包括疼痛的视觉模拟评分(VRS)、血压、副作用、2天内的并发症以及总体满意度评分。

结果

补充镇痛药的使用频率(两次或更频繁)或VRS方面没有差异。TEB组(n = 7/33)低血压的发生频率明显高于PVB组(n = 1/36)(P = 0.02);另一方面,恶心呕吐和瘙痒的发生率以及总体满意度评分相似。两组均无并发症;然而,PVB组有4例患者的导管向胸腔内移位。

结论

与TEB相比,USG-PVB实现了相似的疼痛缓解并降低了低血压的发生率。我们得出结论,相同浓度的罗哌卡因和芬太尼进行的两种阻滞均可为VATS提供充分的术后镇痛。

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本文引用的文献

1
Ultrasound-guided thoracic paravertebral blockade: a cadaveric study.超声引导胸椎旁神经阻滞:尸体研究。
Anesth Analg. 2010 Jun 1;110(6):1735-9. doi: 10.1213/ANE.0b013e3181dd58b0. Epub 2010 Apr 30.
2
Efficacy and safety of different techniques of paravertebral block for analgesia after thoracotomy: a systematic review and metaregression.开胸术后不同椎旁阻滞技术用于镇痛的有效性和安全性:一项系统评价和Meta回归分析
Br J Anaesth. 2009 Nov;103(5):626-36. doi: 10.1093/bja/aep272.
3
Ultrasound-guided paravertebral puncture and placement of catheters in human cadavers: an imaging study.
Risk and benefit analysis of single-shot nerve block for postoperative analgesia for uniportal video-assisted thoracic surgery (uVATS): a randomized controlled trial.
单剂量神经阻滞用于单孔电视辅助胸腔镜手术(uVATS)术后镇痛的风险与效益分析:一项随机对照试验
BMC Anesthesiol. 2025 Feb 12;25(1):68. doi: 10.1186/s12871-025-02955-w.
4
Erector spinae plane block did not improve postoperative pain-related outcomes and recovery after video-assisted thoracoscopic surgery : a randomised controlled double-blinded multi-center trial.竖脊肌平面阻滞不能改善电视辅助胸腔镜手术后与疼痛相关的术后结局及恢复情况:一项随机对照双盲多中心试验。
BMC Anesthesiol. 2024 Apr 23;24(1):156. doi: 10.1186/s12871-024-02544-3.
5
The association of regional block with intraoperative opioid consumption in patients undergoing video-assisted thoracoscopic surgery: a single-center, retrospective study.区域阻滞与接受电视辅助胸腔镜手术患者术中阿片类药物消耗的关联:一项单中心回顾性研究。
J Cardiothorac Surg. 2024 Mar 13;19(1):124. doi: 10.1186/s13019-024-02611-3.
6
Post-Operative Thoracic Epidural Analgesia and Incidence of Major Complications according to Specific Safety Standardized Documentation: A Large Retrospective Dual Center Experience.根据特定安全标准化文件的术后胸段硬膜外镇痛及主要并发症发生率:一项大型回顾性双中心经验
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7
Intraoperative Sufentanil Consumption and the Risk of Postoperative Nausea and/or Vomiting: A Retrospective Observational Study.术中舒芬太尼用量与术后恶心和/或呕吐风险:一项回顾性观察研究。
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8
Local anesthetic dosing and toxicity of adult truncal catheters: a narrative review of published practice.成人躯干导管的局部麻醉剂剂量和毒性:已发表实践的叙述性综述。
Reg Anesth Pain Med. 2024 Mar 4;49(3):209-222. doi: 10.1136/rapm-2023-104667.
9
Application of laryngeal mask airway anesthesia with preserved spontaneous breathing in children undergoing video-assisted thoracic surgery.保留自主呼吸的喉罩气道麻醉在小儿电视辅助胸腔镜手术中的应用
Front Pediatr. 2023 Mar 10;11:933158. doi: 10.3389/fped.2023.933158. eCollection 2023.
10
Do we still need thoracic epidural analgesia in minimally invasive lung surgery?在微创肺手术中我们仍需要胸段硬膜外镇痛吗?
J Thorac Dis. 2022 Sep;14(9):3105-3107. doi: 10.21037/jtd-2022-14.
超声引导下在人体尸体中进行椎旁穿刺及导管置入:一项影像学研究
Br J Anaesth. 2009 Apr;102(4):534-9. doi: 10.1093/bja/aep015. Epub 2009 Feb 24.
4
A systematic review of randomized trials evaluating regional techniques for postthoracotomy analgesia.一项对评估开胸术后镇痛区域技术的随机试验的系统评价。
Anesth Analg. 2008 Sep;107(3):1026-40. doi: 10.1213/01.ane.0000333274.63501.ff.
5
The site of action of epidurally administered opioids and its relevance to postoperative pain management.硬膜外给药阿片类药物的作用部位及其与术后疼痛管理的相关性。
Anaesthesia. 2006 Jul;61(7):659-64. doi: 10.1111/j.1365-2044.2006.04713.x.
6
A comparison of the analgesic efficacy and side-effects of paravertebral vs epidural blockade for thoracotomy--a systematic review and meta-analysis of randomized trials.开胸手术中椎旁阻滞与硬膜外阻滞镇痛效果及副作用的比较——随机试验的系统评价和荟萃分析
Br J Anaesth. 2006 Apr;96(4):418-26. doi: 10.1093/bja/ael020. Epub 2006 Feb 13.
7
The site of action of epidural fentanyl in humans: the difference between infusion and bolus administration.硬膜外注射芬太尼在人体中的作用部位:输注与推注给药的差异。
Anesth Analg. 2003 Nov;97(5):1428-1438. doi: 10.1213/01.ANE.0000081793.60059.10.
8
A randomized, double-blinded comparison of thoracic epidural ropivacaine, ropivacaine/fentanyl, or bupivacaine/fentanyl for postthoracotomy analgesia.罗哌卡因、罗哌卡因/芬太尼或布比卡因/芬太尼用于开胸术后镇痛的随机双盲比较
Anesth Analg. 2002 Nov;95(5):1344-50, table of contents. doi: 10.1097/00000539-200211000-00046.
9
A prospective, randomized comparison of preoperative and continuous balanced epidural or paravertebral bupivacaine on post-thoracotomy pain, pulmonary function and stress responses.术前及持续平衡硬膜外或椎旁注射布比卡因对开胸术后疼痛、肺功能及应激反应影响的前瞻性随机对照研究
Br J Anaesth. 1999 Sep;83(3):387-92. doi: 10.1093/bja/83.3.387.
10
Continuous paravertebral extrapleural infusion for post-thoracotomy pain management.连续椎旁胸膜外输注用于开胸术后疼痛管理。
Surgery. 1999 Oct;126(4):650-6; discussion 656-7.