用巨细胞病毒免疫球蛋白联合更昔洛韦治疗骨髓移植后的巨细胞病毒肺炎。
Treatment of cytomegalovirus pneumonia after bone marrow transplantation with cytomegalovirus immunoglobulin combined with ganciclovir.
作者信息
Verdonck L F, de Gast G C, Dekker A W, de Weger R A, Schuurman H J, Rozenberg-Arska M
机构信息
Department of Haematology, University Hospital, Utrecht, The Netherlands.
出版信息
Bone Marrow Transplant. 1989 Mar;4(2):187-9.
We studied the effect of cytomegalovirus immunoglobulin alone, or combined with ganciclovir, on the outcome of biopsy proven cytomegalovirus pneumonia after bone marrow transplantation. Treatment with cytomegalovirus immunoglobulin alone had no effect on the cytomegalovirus nor on clinical outcome. The combined treatment of cytomegalovirus immunoglobulin with ganciclovir suppressed the cytomegalovirus but all patients died because of ongoing pulmonary deterioration. These results may suggest that this combined treatment has limited value on the outcome of an established cytomegalovirus pneumonia after marrow transplantation.
我们研究了单独使用巨细胞病毒免疫球蛋白或联合更昔洛韦对骨髓移植后经活检证实的巨细胞病毒肺炎预后的影响。单独使用巨细胞病毒免疫球蛋白治疗对巨细胞病毒及临床预后均无影响。巨细胞病毒免疫球蛋白与更昔洛韦联合治疗可抑制巨细胞病毒，但所有患者均因肺部持续恶化而死亡。这些结果可能表明，这种联合治疗对骨髓移植后已确诊的巨细胞病毒肺炎的预后价值有限。
Zotero 插件