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全腹腔镜手术与腹腔镜辅助远端胃癌切除术治疗胃癌的比较:基于日本和韩国文献的Meta分析

Comparison between total laparoscopy and laparoscopy-assisted distal gastrectomy for gastric cancer. A meta-analysis based on Japanese and Korean articles.

作者信息

Xiao Shuo-Meng, Gao Xiao-Jin, Zhao Ping

机构信息

Department of Gastro-Hepatic Surgery, Sichuan Cancer Hospital, Chengdu, China. E-mail.

出版信息

Saudi Med J. 2014 Nov;35(11):1318-23.

Abstract

OBJECTIVES

To assess the safety and feasibility of total laparoscopy distal gastrectomy (TLDG).

METHODS

This meta-analysis was conducted between April and July 2013 in Sichuan Cancer Hospital, Chengdu, China. We searched PubMed, EMBASE and China Knowledge Resource Integrated Database updated until May 2013. Eight retrospective studies and one prospective study involving 2,046 total patients were included.

RESULTS

The results showed that TLDG was associated with lower blood loss (mean difference=-22.39, p=0.04). and a greater number of harvested lymph nodes (mean difference=2.74, p=0.02). There was no significant difference between the 2 groups in operation time, time to first flatus, length of postoperative hospital stay, and postoperative complications.

CONCLUSION

Compared with laparoscopy-assisted distal gastrectomy, TLDG resulted in reduced blood loss, and a greater number of harvested lymph nodes. Total laparoscopy distal gastrectomy is safe and feasible for gastric cancer.

摘要

目的

评估全腹腔镜远端胃癌切除术(TLDG)的安全性和可行性。

方法

本荟萃分析于2013年4月至7月在中国成都的四川省肿瘤医院进行。我们检索了截至2013年5月更新的PubMed、EMBASE和中国知网数据库。纳入了8项回顾性研究和1项前瞻性研究,共涉及2046例患者。

结果

结果显示,TLDG与较少的失血量相关(平均差异=-22.39,p=0.04),以及更多的淋巴结清扫数量(平均差异=2.74,p=0.02)。两组在手术时间、首次排气时间、术后住院时间和术后并发症方面无显著差异。

结论

与腹腔镜辅助远端胃癌切除术相比,TLDG导致失血量减少,淋巴结清扫数量增加。全腹腔镜远端胃癌切除术对胃癌患者是安全可行的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/365f/4362143/d05bf9a661fd/SaudiMedJ-35-1318-g001.jpg

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