免疫突触的脂质基模式形成
Lipid-based patterning of the immunological synapse.
作者信息
Huse Morgan
机构信息
*Immunology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, U.S.A.
出版信息
Biochem Soc Trans. 2014 Dec;42(6):1506-11. doi: 10.1042/BST20140191.
Abstract
The immunological synapse controls T-lymphocyte function by polarizing effector responses towards the antigen-presenting cell. In this review, I discuss the molecular pathways required for synapse assembly, focusing on the central roles played by lipid second-messenger signalling.
摘要
免疫突触通过使效应反应朝向抗原呈递细胞极化来控制T淋巴细胞功能。在这篇综述中，我将讨论突触组装所需的分子途径，重点关注脂质第二信使信号传导所起的核心作用。
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