证明药物遗传学检测临床实用性所需的证据：争议仍在继续。
Evidence required to demonstrate clinical utility of pharmacogenetic testing: the debate continues.
机构信息
Center for Pharmacogenomics and Individualized Therapy, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, USA.
1] Center for Pharmacogenomics and Individualized Therapy, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, USA [2] Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
出版信息
Clin Pharmacol Ther. 2014 Dec;96(6):655-7. doi: 10.1038/clpt.2014.185.
Pharmacogenetics is an area of research that has potential to greatly benefit patients. However, the routine use of diagnostic pharmacogenetic testing to inform treatment decisions is limited. Here we discuss the determination of clinical utility of pharmacogenetic testing and the level of evidence required to support translation into clinical practice.
药物遗传学是一个具有巨大潜力可以使患者受益的研究领域。然而，常规使用诊断性药物遗传学检测来为治疗决策提供信息的做法受到限制。在这里，我们讨论了确定药物遗传学检测的临床实用性以及支持其转化为临床实践所需的证据水平。
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