• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大豆婴儿配方奶粉可能与自闭症行为有关。

Soy Infant Formula may be Associated with Autistic Behaviors.

作者信息

Westmark Cara J

机构信息

Department of Neurology, University of Wisconsin, USA.

出版信息

Autism Open Access. 2013 Nov 18;3. doi: 10.4172/2165-7890.1000120.

DOI:10.4172/2165-7890.1000120
PMID:25401047
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4229689/
Abstract

The effects of soy-based infant formulas on childhood development are not well understood. This exploratory study evaluates the severity of autistic behaviors in association with the use of soy-based infant formula in a population of high-functioning autistic children. Medical record data were analyzed from the Simons Foundation Autism Research Initiative Simplex Collection, which included data on infant formula use and autism diagnostic scores for 1,949 autistic children. We found exploratory associations between the use of soy-based infant formula and several autistic behaviors as assessed by line-item analysis of the Aberrant Behavior Checklist, Autism Diagnostic Interview-Revised and Autism Diagnostic Observation Schedule. This study provides preliminary data that the use of soy-based infant formula may be associated with specific autistic behaviors.

摘要

大豆基婴儿配方奶粉对儿童发育的影响尚未得到充分了解。这项探索性研究评估了在一群高功能自闭症儿童中,使用大豆基婴儿配方奶粉与自闭症行为严重程度之间的关联。对西蒙斯基金会自闭症研究计划单纯型数据集的病历数据进行了分析,该数据集包括1949名自闭症儿童的婴儿配方奶粉使用情况和自闭症诊断评分数据。通过对异常行为检查表、自闭症诊断访谈修订版和自闭症诊断观察量表的逐项目分析,我们发现使用大豆基婴儿配方奶粉与几种自闭症行为之间存在探索性关联。这项研究提供了初步数据,表明使用大豆基婴儿配方奶粉可能与特定的自闭症行为有关。

相似文献

1
Soy Infant Formula may be Associated with Autistic Behaviors.大豆婴儿配方奶粉可能与自闭症行为有关。
Autism Open Access. 2013 Nov 18;3. doi: 10.4172/2165-7890.1000120.
2
Soy infant formula and seizures in children with autism: a retrospective study.大豆婴儿配方奶粉与自闭症儿童的癫痫发作:一项回顾性研究。
PLoS One. 2014 Mar 12;9(3):e80488. doi: 10.1371/journal.pone.0080488. eCollection 2014.
3
Parental Reports on Early Autism Behaviors in Their Children with Fragile X Syndrome as a Function of Infant Feeding.家长报告脆性 X 综合征患儿的早期自闭症行为与婴儿喂养的关系
Nutrients. 2021 Aug 22;13(8):2888. doi: 10.3390/nu13082888.
4
Soy-Based Infant Formula is Associated with an Increased Prevalence of Comorbidities in Fragile X Syndrome.以大豆为基础的婴儿配方奶粉与脆性 X 综合征合并症的患病率增加有关。
Nutrients. 2020 Oct 14;12(10):3136. doi: 10.3390/nu12103136.
5
Lactose-Free Milk or Soy-Based Formulas Do Not Improve Caregivers' Distress or Perceptions of Difficult Infant Behavior.无乳糖牛奶或大豆基配方奶粉并不能改善照顾者的困扰或对婴儿难养行为的认知。
J Pediatr Gastroenterol Nutr. 2015 Jul;61(1):119-24. doi: 10.1097/MPG.0000000000000743.
6
A modified screening tool for autism (Checklist for Autism in Toddlers [CHAT-23]) for Chinese children.一种针对中国儿童的改良版自闭症筛查工具(幼儿自闭症筛查清单[CHAT-23])。
Pediatrics. 2004 Aug;114(2):e166-76. doi: 10.1542/peds.114.2.e166.
7
Soy formula for prevention of allergy and food intolerance in infants.用于预防婴儿过敏和食物不耐受的大豆配方奶粉。
Cochrane Database Syst Rev. 2004(3):CD003741. doi: 10.1002/14651858.CD003741.pub2.
8
A hypothesis regarding the molecular mechanism underlying dietary soy-induced effects on seizure propensity.关于膳食大豆对癫痫易感性影响的分子机制的一种假说。
Front Neurol. 2014 Sep 3;5:169. doi: 10.3389/fneur.2014.00169. eCollection 2014.
9
Prenatal, perinatal, and neonatal factors in autism, pervasive developmental disorder-not otherwise specified, and the general population.自闭症、未特定的广泛性发育障碍及普通人群中的产前、围产期和新生儿因素。
Pediatrics. 2001 Apr;107(4):E63. doi: 10.1542/peds.107.4.e63.
10
[ADI-R and ADOS and the differential diagnosis of autism spectrum disorders: Interests, limits and openings].[《孤独症诊断访谈修订版(ADI-R)与孤独症诊断观察量表(ADOS)及孤独症谱系障碍的鉴别诊断:意义、局限与展望》]
Encephale. 2019 Nov;45(5):441-448. doi: 10.1016/j.encep.2019.07.002. Epub 2019 Sep 5.

引用本文的文献

1
Soy Protein Isolate Affects Blood and Brain Biomarker Expression in a Mouse Model of Fragile X.大豆分离蛋白对脆性X小鼠模型的血液和脑生物标志物表达有影响。
Int J Mol Sci. 2025 Jun 26;26(13):6137. doi: 10.3390/ijms26136137.
2
The role of nutrition and gut microbiome in childhood brain development and behavior.营养与肠道微生物群在儿童大脑发育和行为中的作用。
Front Nutr. 2025 Jun 9;12:1590172. doi: 10.3389/fnut.2025.1590172. eCollection 2025.
3
Soy-based purified ingredient diet affects mouse gut permeability and the microbiome in fragile X mice.大豆基纯化成分饮食会影响脆性X小鼠的肠道通透性和微生物群。
Front Mol Neurosci. 2025 Mar 21;18:1520211. doi: 10.3389/fnmol.2025.1520211. eCollection 2025.
4
Effects of Soy Protein Isolate on Fragile X Phenotypes in Mice.大豆分离蛋白对脆性 X 表型小鼠的影响。
Nutrients. 2024 Jan 18;16(2):284. doi: 10.3390/nu16020284.
5
On-Tissue Spatial Proteomics Integrating MALDI-MS Imaging with Shotgun Proteomics Reveals Soy Consumption-Induced Protein Changes in a Fragile X Syndrome Mouse Model.基于 MALDI-MS 成像的组织原位空间蛋白质组学与鸟枪法蛋白质组学整合揭示了脆性 X 综合征小鼠模型中大豆摄入诱导的蛋白质变化。
ACS Chem Neurosci. 2024 Jan 3;15(1):119-133. doi: 10.1021/acschemneuro.3c00497. Epub 2023 Dec 18.
6
Diet in treatment of autism spectrum disorders.饮食在自闭症谱系障碍治疗中的应用
Front Neurosci. 2023 Jul 10;16:1031016. doi: 10.3389/fnins.2022.1031016. eCollection 2022.
7
Improving Reproducibility to Enhance Scientific Rigor through Consideration of Mouse Diet.通过考虑小鼠饮食提高可重复性以增强科学严谨性。
Animals (Basel). 2022 Dec 7;12(24):3448. doi: 10.3390/ani12243448.
8
Effects of Soy-Based Infant Formula on Weight Gain and Neurodevelopment in an Autism Mouse Model.大豆配方婴儿配方对自闭症小鼠模型体重增加和神经发育的影响。
Cells. 2022 Apr 15;11(8):1350. doi: 10.3390/cells11081350.
9
S3 guideline Allergy Prevention.S3 预防过敏指南。
Allergol Select. 2022 Mar 4;6:61-97. doi: 10.5414/ALX02303E. eCollection 2022.
10
Parental Reports on Early Autism Behaviors in Their Children with Fragile X Syndrome as a Function of Infant Feeding.家长报告脆性 X 综合征患儿的早期自闭症行为与婴儿喂养的关系
Nutrients. 2021 Aug 22;13(8):2888. doi: 10.3390/nu13082888.

本文引用的文献

1
Soy infant formula and seizures in children with autism: a retrospective study.大豆婴儿配方奶粉与自闭症儿童的癫痫发作:一项回顾性研究。
PLoS One. 2014 Mar 12;9(3):e80488. doi: 10.1371/journal.pone.0080488. eCollection 2014.
2
Soy-based diet exacerbates seizures in mouse models of neurological disease.基于大豆的饮食会加重神经疾病小鼠模型中的癫痫发作。
J Alzheimers Dis. 2013;33(3):797-805. doi: 10.3233/JAD-2012-121426.
3
Early identification of autism in fragile X syndrome: a review.脆性 X 综合征中自闭症的早期识别:综述。
J Intellect Disabil Res. 2013 Sep;57(9):803-14. doi: 10.1111/j.1365-2788.2012.01609.x. Epub 2012 Sep 14.
4
Developmental status of 1-year-old infants fed breast milk, cow's milk formula, or soy formula.1 岁婴儿母乳喂养、牛奶配方或大豆配方的发育状况。
Pediatrics. 2012 Jun;129(6):1134-40. doi: 10.1542/peds.2011-3121. Epub 2012 May 28.
5
Prevalence of autism spectrum disorders--Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008.自闭症谱系障碍的流行率——自闭症及发展障碍监测网络,美国 14 个监测点,2008 年。
MMWR Surveill Summ. 2012 Mar 30;61(3):1-19.
6
NTP-CERHR expert panel report on the developmental toxicity of soy infant formula.美国国家毒理学计划-发育毒性风险评估委员会关于大豆婴儿配方奶粉发育毒性的专家小组报告。
Birth Defects Res B Dev Reprod Toxicol. 2011 Oct;92(5):421-68. doi: 10.1002/bdrb.20314. Epub 2011 Sep 21.
7
Early-life soy exposure and gender-role play behavior in children.儿童早期大豆暴露与性别角色行为。
Environ Health Perspect. 2011 Dec;119(12):1811-6. doi: 10.1289/ehp.1103579. Epub 2011 Aug 3.
8
Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses.修饰 Fmr1KO 小鼠的行为表型:遗传背景差异揭示类似自闭症的反应。
Autism Res. 2011 Feb;4(1):40-56. doi: 10.1002/aur.168. Epub 2011 Jan 25.
9
Cortical responses to speech sounds in 3- and 6-month-old infants fed breast milk, milk formula, or soy formula.对母乳喂养、奶粉喂养或豆奶喂养的3个月和6个月大婴儿的语音的皮质反应。
Dev Neuropsychol. 2010;35(6):762-84. doi: 10.1080/87565641.2010.508547.
10
The Simons Simplex Collection: a resource for identification of autism genetic risk factors.西蒙斯单体型收藏:一个用于鉴定自闭症遗传风险因素的资源。
Neuron. 2010 Oct 21;68(2):192-5. doi: 10.1016/j.neuron.2010.10.006.